Taxonomy for colorectal cancer screening promotion: Lessons from recent randomized controlled trials

Paul Ritvo, Ronald E. Myers, Mardie Serenity, Samir Gupta, John M. Inadomi, Beverly B. Green, Anthony F Jerant, Jill Tinmouth, Lawrence Paszat, Meysam Pirbaglou, Linda Rabeneck

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Objective: To derive a taxonomy for colorectal cancer screening that advances Randomized Controlled Trials (RCTs) and screening uptake. Design: Detailed publication review, multiple interviews with principal investigators (PIs) and collaboration with PIs as co-authors produced a CRCS intervention taxonomy. Semi-structured interview questions with PIs (Drs. Inadomi, Myers, Green, Gupta, Jerant and Ritvo) yielded details about trial conduct. Interview comparisons led to an iterative process informing serial interviews until a consensus was obtained on final taxonomy structure. Results: These taxonomy headings (Engagement Sponsor, Population Targeted, Alternative Screening Tests, Delivery Methods, and Support for Test Performance (EPADS)) were used to compare studies. Exemplary insights emphasized: 1) direct test delivery to patients; 2) linguistic-ethnic matching of staff to minority subjects; and 3) authorization of navigators to schedule or refer for colonoscopies and/or distribute stool blood tests during screening promotion. Conclusion: PIs of key RCTs (2012-2015) derived a CRCS taxonomy useful in detailed examination of CRCS promotion and design of future RCTs.

Original languageEnglish (US)
JournalPreventive Medicine
StateAccepted/In press - May 8 2016


  • Cancer prevention
  • Clinical trials
  • Colorectal cancer
  • Colorectal cancer screening
  • Health service research

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health


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