T-cell chronic lymphocytic leukemia in a double yellow-headed amazon parrot (Amazona ochrocephala oratrix)

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6 Citations (Scopus)

Abstract

An adult, male double yellow-headed Amazon parrot (Amazona ochrocephala oratrix) was diagnosed with chronic lymphocytic leukemia based on results of a complete blood cell count and cytologic examination of a bone marrow aspirate. Treatment with oral chlorambucil was attempted, but no response was evident after 40 days. The bird was euthanatized, and the diagnosis of chronic lymphocytic leukemia was confirmed on gross and microscopic examination of tissues. Neoplastic lymphocytes were found in the bone marrow, liver, kidney, testes, and blood vessels. Based on CD3-positive immunocytochemical and immunohistochemical immunophenotyping, the chronic lymphocytic leukemia was determined to be of T-cell origin.

Original languageEnglish (US)
Pages (from-to)286-294
Number of pages9
JournalJournal of Avian Medicine and Surgery
Volume25
Issue number4
DOIs
StatePublished - Dec 2011

Fingerprint

T-Cell Prolymphocytic Leukemia
Amazona
lymphocytic leukemia
parrots
B-Cell Chronic Lymphocytic Leukemia
Blood Cell Count
T-lymphocytes
bone marrow
Bone Marrow Examination
Chlorambucil
Immunophenotyping
blood cell counts
blood vessels
Birds
Blood Vessels
Testis
mouth
testes
lymphocytes
Bone Marrow

Keywords

  • Amazon parrot
  • Amazona ochrocephala oratrix
  • avian
  • chemotherapy
  • chlorambucil
  • chronic lymphocytic leukemia
  • T-cell

ASJC Scopus subject areas

  • Small Animals

Cite this

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abstract = "An adult, male double yellow-headed Amazon parrot (Amazona ochrocephala oratrix) was diagnosed with chronic lymphocytic leukemia based on results of a complete blood cell count and cytologic examination of a bone marrow aspirate. Treatment with oral chlorambucil was attempted, but no response was evident after 40 days. The bird was euthanatized, and the diagnosis of chronic lymphocytic leukemia was confirmed on gross and microscopic examination of tissues. Neoplastic lymphocytes were found in the bone marrow, liver, kidney, testes, and blood vessels. Based on CD3-positive immunocytochemical and immunohistochemical immunophenotyping, the chronic lymphocytic leukemia was determined to be of T-cell origin.",
keywords = "Amazon parrot, Amazona ochrocephala oratrix, avian, chemotherapy, chlorambucil, chronic lymphocytic leukemia, T-cell",
author = "Anna Osofsky and Michelle Hawkins and Oded Foreman and Kent, {Michael S} and William Vernau and Lowenstine, {Linda J}",
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T1 - T-cell chronic lymphocytic leukemia in a double yellow-headed amazon parrot (Amazona ochrocephala oratrix)

AU - Osofsky, Anna

AU - Hawkins, Michelle

AU - Foreman, Oded

AU - Kent, Michael S

AU - Vernau, William

AU - Lowenstine, Linda J

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