Systemic acanthamoebiasis associated with canine distemper in dogs in the semiarid region of Paraíba, Brazil

Maria T S Frade, Luiza F. de Melo, Clarice R M Pessoa, Jeann L. de Araújo, Rafael A. Fighera, Almir P. Souza, Francisco A Uzal, Antonio F M Dantas

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Infections by free-living amoebae can cause systemic disease in animals and humans. We describe the epidemiological, clinical and pathological aspects of disseminated acanthamoebiasis associated with canine distemper in three dogs of the semiarid region of Paraíba, Northeastern Brazil. Affected dogs developed progressive neurological and respiratory signs that progressed to death within in two to 20 days. Gross lesions were irregular and with yellow- -reddish nodules randomly distributed in the lungs, heart, kidneys, spleen, lymph nodes, adrenals, and intestine. One dog had foci of malacia in the parietal cortex and another one in nucleus of brain basis. Histologically, pyogranulomas with areas of necrosis and hemorrhage in all organs affected were observed, associated with myriads of intralesional amoebic trophozoites. All three cases were concomitant canine distemper, that possibly triggered immunosuppression in the dogs. The diagnosis was performed through microscopic findings of infection by free-living amoebae and confirmed Acanthamoeba sp. by immunohistochemistry.

Original languageEnglish (US)
Pages (from-to)160-164
Number of pages5
JournalPesquisa Veterinaria Brasileira
Volume35
Issue number2
DOIs
StatePublished - 2015

Fingerprint

Distemper
canine distemper
Brazil
Dogs
Amoeba
dogs
Acanthamoeba
diseases and disorders (animals and humans)
Trophozoites
Animal Diseases
Parietal Lobe
trophozoites
immunosuppression
Infection
lesions (animal)
infection
Immunosuppression
Intestines
hemorrhage
immunohistochemistry

Keywords

  • Acanthamoeba sp.
  • Amebiasis
  • Canine distemper
  • Diseases of dogs
  • Opportunistic diseases

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Frade, M. T. S., de Melo, L. F., Pessoa, C. R. M., de Araújo, J. L., Fighera, R. A., Souza, A. P., ... Dantas, A. F. M. (2015). Systemic acanthamoebiasis associated with canine distemper in dogs in the semiarid region of Paraíba, Brazil. Pesquisa Veterinaria Brasileira, 35(2), 160-164. https://doi.org/10.1590/S0100-736X2015000200011

Systemic acanthamoebiasis associated with canine distemper in dogs in the semiarid region of Paraíba, Brazil. / Frade, Maria T S; de Melo, Luiza F.; Pessoa, Clarice R M; de Araújo, Jeann L.; Fighera, Rafael A.; Souza, Almir P.; Uzal, Francisco A; Dantas, Antonio F M.

In: Pesquisa Veterinaria Brasileira, Vol. 35, No. 2, 2015, p. 160-164.

Research output: Contribution to journalArticle

Frade, MTS, de Melo, LF, Pessoa, CRM, de Araújo, JL, Fighera, RA, Souza, AP, Uzal, FA & Dantas, AFM 2015, 'Systemic acanthamoebiasis associated with canine distemper in dogs in the semiarid region of Paraíba, Brazil', Pesquisa Veterinaria Brasileira, vol. 35, no. 2, pp. 160-164. https://doi.org/10.1590/S0100-736X2015000200011
Frade, Maria T S ; de Melo, Luiza F. ; Pessoa, Clarice R M ; de Araújo, Jeann L. ; Fighera, Rafael A. ; Souza, Almir P. ; Uzal, Francisco A ; Dantas, Antonio F M. / Systemic acanthamoebiasis associated with canine distemper in dogs in the semiarid region of Paraíba, Brazil. In: Pesquisa Veterinaria Brasileira. 2015 ; Vol. 35, No. 2. pp. 160-164.
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