Systematic review of the use of platelet-rich plasma in aesthetic dermatology

Michael S. Leo, Alur S. Kumar, Raj Kirit, Rajyalaxmi Konathan, Raja K Sivamani

Research output: Contribution to journalReview article

41 Citations (Scopus)

Abstract

Summary: Platelet-rich plasma (PRP) is a highly concentrated autologous solution of plasma prepared from a patient's own blood. PRP contains platelets that are purported to release numerous growth factors that may be valuable in numerous dermatologic applications. Here, we review systematically the clinical cosmetic applications of PRP including: androgenetic alopecia, scar revision, acne scars, skin rejuvenation, dermal augmentation, and striae distensae to understand the potential and best practices for PRP use. A systematic search was conducted on three databases: Pubmed, Embase, and Web of Science. Publications were included if they were in English, investigated the clinical applications of PRP in aesthetic dermatology and reported clinical results either as case reports or clinical studies. There were a total of 22 manuscripts that fulfilled these criteria. Four evaluated hair-related applications, eight evaluated the treatment of scars and postprocedure recovery, eight evaluated skin rejuvenation and dermal augmentation, and two evaluated treatment of striae distensae. PRP is a relatively new treatment modality with studies suggesting its utility in aesthetic dermatology. The combination of PRP with other therapies is particularly interesting. Future studies should include controls, including incorporation of split-face comparisons, to reduce intersubject variability.

Original languageEnglish (US)
Pages (from-to)315-323
Number of pages9
JournalJournal of Cosmetic Dermatology
Volume14
Issue number4
DOIs
StatePublished - Dec 1 2015

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Platelet-Rich Plasma
Dermatology
Esthetics
Striae Distensae
Cicatrix
Rejuvenation
Skin
Manuscripts
Alopecia
Acne Vulgaris
Therapeutics
Practice Guidelines
PubMed
Cosmetics
Hair
Publications
Intercellular Signaling Peptides and Proteins
Blood Platelets
Databases

Keywords

  • Aesthetic
  • Cosmetic
  • Dermatology
  • Facial rejuvenation
  • Platelet-rich plasma
  • Review

ASJC Scopus subject areas

  • Dermatology

Cite this

Systematic review of the use of platelet-rich plasma in aesthetic dermatology. / Leo, Michael S.; Kumar, Alur S.; Kirit, Raj; Konathan, Rajyalaxmi; Sivamani, Raja K.

In: Journal of Cosmetic Dermatology, Vol. 14, No. 4, 01.12.2015, p. 315-323.

Research output: Contribution to journalReview article

Leo, Michael S. ; Kumar, Alur S. ; Kirit, Raj ; Konathan, Rajyalaxmi ; Sivamani, Raja K. / Systematic review of the use of platelet-rich plasma in aesthetic dermatology. In: Journal of Cosmetic Dermatology. 2015 ; Vol. 14, No. 4. pp. 315-323.
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