Systematic review of single stage revision for prosthetic joint infection

Zachary C. Lum, Christopher Thomas Holland, John P. Meehan

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


While advanced technology, increased medical knowledge and improved surgical technique has improved patient outcomes in total joint arthroplasty, prosthetic joint infection still remains one of the leading causes of increased healthcare costs, medical resources and societal burdens in orthopaedic care. Two stage arthroplasty revision remains the gold standard for treatment of prosthetic joint infection. Proponents of single stage revision arthroplasty for infection argue that it results in lower healthcare costs while improving patient reported functional outcomes and with equivalent success rates. Here we review the history of single stage revision arthroplasty, discuss the key principles, highlight the indications and contraindications, and review the reported outcomes with a focus on future developments of single stage revision arthroplasty for hip and knee periprosthetic joint infections.

Original languageEnglish (US)
Pages (from-to)559-572
Number of pages14
JournalWorld Journal of Orthopaedics
Issue number12
StatePublished - Dec 1 2020


  • Infection
  • Prosthetic joint infection
  • Revision total joint arthroplasty
  • Single stage
  • Total knee arthroplasty

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


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