Synthesis of 13C1-pinonaldehyde

Christopher W. Dicus, Dan Willenbring, Michael H. Nantz

Research output: Contribution to journalArticle

3 Scopus citations


13C1-pinonaldehyde is prepared in seven steps from cis-pinonic acid. In the key sequence, the introduction of labeled carbon is accomplished by Lieben degradation of a methyl ketone followed by treatment of the resultant carboxylic acid with 13C-methyl lithium.

Original languageEnglish (US)
Pages (from-to)223-229
Number of pages7
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Issue number3
StatePublished - Mar 2005


  • Carbon-13
  • Lieben degradation
  • Pinonaldehyde

ASJC Scopus subject areas

  • Analytical Chemistry
  • Drug Discovery
  • Organic Chemistry
  • Clinical Biochemistry
  • Molecular Medicine
  • Pharmacology

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