Synthesis of 13C1-pinonaldehyde

Christopher W. Dicus, Dan Willenbring, Michael H. Nantz

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

13C1-pinonaldehyde is prepared in seven steps from cis-pinonic acid. In the key sequence, the introduction of labeled carbon is accomplished by Lieben degradation of a methyl ketone followed by treatment of the resultant carboxylic acid with 13C-methyl lithium.

Original languageEnglish (US)
Pages (from-to)223-229
Number of pages7
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume48
Issue number3
DOIs
StatePublished - Mar 2005

Fingerprint

NSC 153174
Carboxylic Acids
Ketones
Lithium
Carbon
Degradation
2,2-dimethyl-3-acetyl-cyclobutyl-ethanal

Keywords

  • Carbon-13
  • Lieben degradation
  • Pinonaldehyde

ASJC Scopus subject areas

  • Analytical Chemistry
  • Drug Discovery
  • Organic Chemistry
  • Clinical Biochemistry
  • Molecular Medicine
  • Pharmacology

Cite this

Synthesis of 13C1-pinonaldehyde. / Dicus, Christopher W.; Willenbring, Dan; Nantz, Michael H.

In: Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 48, No. 3, 03.2005, p. 223-229.

Research output: Contribution to journalArticle

Dicus, CW, Willenbring, D & Nantz, MH 2005, 'Synthesis of 13C1-pinonaldehyde', Journal of Labelled Compounds and Radiopharmaceuticals, vol. 48, no. 3, pp. 223-229. https://doi.org/10.1002/jlcr.910
Dicus, Christopher W. ; Willenbring, Dan ; Nantz, Michael H. / Synthesis of 13C1-pinonaldehyde. In: Journal of Labelled Compounds and Radiopharmaceuticals. 2005 ; Vol. 48, No. 3. pp. 223-229.
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