Synthesis of sulfated β-1,6-linked oligosaccharide mimetics

A novel potent inhibitor of HIV replication

Yoshitomo Suhara, Mie Ichikawa, James Hildreth, Yoshitaka Ichikawa

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

A novel sulfated β(1→6)-linked oligosaccharide mimetics has been synthesized and found to be a potent inhibitor of HIV replication, with an IC50 of 1 μM.

Original languageEnglish (US)
Pages (from-to)2549-2552
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number15
DOIs
StatePublished - Apr 8 1996
Externally publishedYes

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Oligosaccharides
Inhibitory Concentration 50
HIV

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthesis of sulfated β-1,6-linked oligosaccharide mimetics : A novel potent inhibitor of HIV replication. / Suhara, Yoshitomo; Ichikawa, Mie; Hildreth, James; Ichikawa, Yoshitaka.

In: Tetrahedron Letters, Vol. 37, No. 15, 08.04.1996, p. 2549-2552.

Research output: Contribution to journalArticle

Suhara, Yoshitomo ; Ichikawa, Mie ; Hildreth, James ; Ichikawa, Yoshitaka. / Synthesis of sulfated β-1,6-linked oligosaccharide mimetics : A novel potent inhibitor of HIV replication. In: Tetrahedron Letters. 1996 ; Vol. 37, No. 15. pp. 2549-2552.
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