Synthesis of ranitidine (Zantac) from cellulose-derived 5-(chloromethyl)furfural

Mark Mascal, Saikat Dutta

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The biomass-derived platform chemical 5-(chloromethyl)furfural is converted into the blockbuster antiulcer drug ranitidine (Zantac) in four steps with an overall 68% isolated yield. This journal is

Original languageEnglish (US)
Pages (from-to)3101-3102
Number of pages2
JournalGreen Chemistry
Volume13
Issue number11
DOIs
StatePublished - Nov 2011

Fingerprint

Furfural
Ranitidine
Cellulose
cellulose
Biomass
drug
biomass
Pharmaceutical Preparations
5-(chloromethyl)furfural
chemical

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution

Cite this

Synthesis of ranitidine (Zantac) from cellulose-derived 5-(chloromethyl)furfural. / Mascal, Mark; Dutta, Saikat.

In: Green Chemistry, Vol. 13, No. 11, 11.2011, p. 3101-3102.

Research output: Contribution to journalArticle

Mascal, Mark ; Dutta, Saikat. / Synthesis of ranitidine (Zantac) from cellulose-derived 5-(chloromethyl)furfural. In: Green Chemistry. 2011 ; Vol. 13, No. 11. pp. 3101-3102.
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