Synthesis of Oligomers Derived from Amide-Linked Neuraminic Acid Analogues

Travis Q. Gregar, Jacquelyn Gervay-Hague

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


N-Fluoren-9-ylmethoxycarbonyl-protected sugar amino acids derived from α-O-methoxy- and 2,3-dehydroneuraminic acids have been prepared. Incorporation of these monomer units into solid-phase synthesis led to the efficient synthesis of two series of oligomers varying from one to eight units in length. The (1-5)-linked amides of 2,3-dehydroneuraminic acid were further subjected to hydrogenation giving a third series of oligomers with a β-hydrido substituent at the anomeric carbon.

Original languageEnglish (US)
Pages (from-to)1001-1009
Number of pages9
JournalJournal of Organic Chemistry
Issue number4
StatePublished - Feb 20 2004

ASJC Scopus subject areas

  • Organic Chemistry


Dive into the research topics of 'Synthesis of Oligomers Derived from Amide-Linked Neuraminic Acid Analogues'. Together they form a unique fingerprint.

Cite this