Synthesis of (Dicarbonyl)(Ƞ5-cyclopentadienyl)Manganese Complex Stabilized Nucleoside Phosphite Esters

Don Bergstrom, Peter Beal, Robert Lind

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We have found that stable nucleoside derived phosphite ester manganese complexes can be generated by the reaction of Mn(CO)2(THF)(Ƞ5-C5H4R) with nucleoside phosphite esters. These complexes appear to be stable towards oxygen and reagents used for DNA synthesis and deprotection. The cyclopentadienyl ligand can be modified by a strong electron withdrawing group and still retain the photochemical and chemical properties necessary to complex readily to phosphite esters.

Original languageEnglish (US)
Pages (from-to)1061-1063
Number of pages3
JournalNucleosides and Nucleotides
Volume8
Issue number5-6
DOIs
StatePublished - Jan 1 1989
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Genetics

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