Abstract
COX metabolites of 8,9-EET, previously observed as potent mitogenic lipid mediators, were synthesized for the first time by using two synthetic approaches. These synthetic materials allow for structural confirmation of COX metabolites of 8,9-EET and further study of their biological roles.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4308-4313 |
| Number of pages | 6 |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 15 |
| Issue number | 20 |
| DOIs | |
| State | Published - 2017 |
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ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
Cite this
Synthesis of cyclooxygenase metabolites of 8,9-epoxyeicosatrienoic acid (EET) : 11- and 15-hydroxy 8,9-EETs. / Barnych, Bogdan; Rand, Amy A.; Cajka, Tomas; Lee, Kin Sing Stephen; Hammock, Bruce D.
In: Organic and Biomolecular Chemistry, Vol. 15, No. 20, 2017, p. 4308-4313.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Synthesis of cyclooxygenase metabolites of 8,9-epoxyeicosatrienoic acid (EET)
T2 - 11- and 15-hydroxy 8,9-EETs
AU - Barnych, Bogdan
AU - Rand, Amy A.
AU - Cajka, Tomas
AU - Lee, Kin Sing Stephen
AU - Hammock, Bruce D.
PY - 2017
Y1 - 2017
N2 - COX metabolites of 8,9-EET, previously observed as potent mitogenic lipid mediators, were synthesized for the first time by using two synthetic approaches. These synthetic materials allow for structural confirmation of COX metabolites of 8,9-EET and further study of their biological roles.
AB - COX metabolites of 8,9-EET, previously observed as potent mitogenic lipid mediators, were synthesized for the first time by using two synthetic approaches. These synthetic materials allow for structural confirmation of COX metabolites of 8,9-EET and further study of their biological roles.
UR - http://www.scopus.com/inward/record.url?scp=85021681542&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85021681542&partnerID=8YFLogxK
U2 - 10.1039/c7ob00789b
DO - 10.1039/c7ob00789b
M3 - Article
AN - SCOPUS:85021681542
VL - 15
SP - 4308
EP - 4313
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
SN - 1477-0520
IS - 20
ER -