Abstract
The lithium acetylide anion of ethyl or methyl propiolate is readily prepared by the addition of n-butyllithium to ethyl or methyl propiolate at low temperature. The anion rapidly adds to a variety of aldehydes or ketones to give ethyl or methyl 4-hydroxy-2-alkynoates in high yield.
Original language | English (US) |
---|---|
Pages (from-to) | 28-29 |
Number of pages | 2 |
Journal | Journal of Organic Chemistry |
Volume | 45 |
Issue number | 1 |
State | Published - 1980 |
ASJC Scopus subject areas
- Organic Chemistry