Abstract
A simple and efficient synthesis of a novel heterobifunctional polyethylene glycol (PEG) spacer is described. The PEG spacer reagent is terminated with aminooxy and bromide functionality for ease of conjugation to a variety of electrophiles and/or nucleophiles.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2821-2823 |
| Number of pages | 3 |
| Journal | Synlett |
| Issue number | 17 |
| DOIs | |
| State | Published - Oct 17 2006 |
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Keywords
- Aminooxy
- Bioconjugation
- Heterobifunctional PEG
- Molecular recognition
- OEG
- Spacer
ASJC Scopus subject areas
- Organic Chemistry
Cite this
Synthesis of a heterobifunctional PEG spacer terminated with aminooxy and bromide functionality. / Dicus, Christopher W.; Nantz, Michael H.
In: Synlett, No. 17, 17.10.2006, p. 2821-2823.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Synthesis of a heterobifunctional PEG spacer terminated with aminooxy and bromide functionality
AU - Dicus, Christopher W.
AU - Nantz, Michael H.
PY - 2006/10/17
Y1 - 2006/10/17
N2 - A simple and efficient synthesis of a novel heterobifunctional polyethylene glycol (PEG) spacer is described. The PEG spacer reagent is terminated with aminooxy and bromide functionality for ease of conjugation to a variety of electrophiles and/or nucleophiles.
AB - A simple and efficient synthesis of a novel heterobifunctional polyethylene glycol (PEG) spacer is described. The PEG spacer reagent is terminated with aminooxy and bromide functionality for ease of conjugation to a variety of electrophiles and/or nucleophiles.
KW - Aminooxy
KW - Bioconjugation
KW - Heterobifunctional PEG
KW - Molecular recognition
KW - OEG
KW - Spacer
UR - http://www.scopus.com/inward/record.url?scp=33750523025&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33750523025&partnerID=8YFLogxK
U2 - 10.1055/s-2006-950246
DO - 10.1055/s-2006-950246
M3 - Article
AN - SCOPUS:33750523025
SP - 2821
EP - 2823
JO - Synlett
JF - Synlett
SN - 0936-5214
IS - 17
ER -