Abstract
A simple and efficient synthesis of a novel heterobifunctional polyethylene glycol (PEG) spacer is described. The PEG spacer reagent is terminated with aminooxy and bromide functionality for ease of conjugation to a variety of electrophiles and/or nucleophiles.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2821-2823 |
| Number of pages | 3 |
| Journal | Synlett |
| Issue number | 17 |
| DOIs | |
| State | Published - Oct 17 2006 |
Keywords
- Aminooxy
- Bioconjugation
- Heterobifunctional PEG
- Molecular recognition
- OEG
- Spacer
ASJC Scopus subject areas
- Organic Chemistry
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Dicus, C. W., & Nantz, M. H. (2006). Synthesis of a heterobifunctional PEG spacer terminated with aminooxy and bromide functionality. Synlett, (17), 2821-2823. https://doi.org/10.1055/s-2006-950246