Abstract
A simple and efficient synthesis of a novel heterobifunctional polyethylene glycol (PEG) spacer is described. The PEG spacer reagent is terminated with aminooxy and bromide functionality for ease of conjugation to a variety of electrophiles and/or nucleophiles.
Original language | English (US) |
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Pages (from-to) | 2821-2823 |
Number of pages | 3 |
Journal | Synlett |
Issue number | 17 |
DOIs | |
State | Published - Oct 17 2006 |
Keywords
- Aminooxy
- Bioconjugation
- Heterobifunctional PEG
- Molecular recognition
- OEG
- Spacer
ASJC Scopus subject areas
- Organic Chemistry