Synthesis of 2H-pyrroles via the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides

Choong Leol Yoo, Marilyn M. Olmstead, Dean J. Tantillo, Mark J. Kurth

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

3,4-Dihydro-2H-pyrrole derivatives were synthesized by the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides. Acrylamide substitution patterns and benzimidoyl chloride equilibration were investigated.

Original languageEnglish (US)
Pages (from-to)477-481
Number of pages5
JournalTetrahedron Letters
Volume47
Issue number4
DOIs
StatePublished - Jan 23 2006

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Acrylamides
Nitriles
Pyrroles
Cycloaddition
Acrylamide
Cycloaddition Reaction
Chlorides
Substitution reactions
Derivatives
delta(1)-pyrroline

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthesis of 2H-pyrroles via the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides. / Yoo, Choong Leol; Olmstead, Marilyn M.; Tantillo, Dean J.; Kurth, Mark J.

In: Tetrahedron Letters, Vol. 47, No. 4, 23.01.2006, p. 477-481.

Research output: Contribution to journalArticle

Yoo, Choong Leol ; Olmstead, Marilyn M. ; Tantillo, Dean J. ; Kurth, Mark J. / Synthesis of 2H-pyrroles via the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides. In: Tetrahedron Letters. 2006 ; Vol. 47, No. 4. pp. 477-481.
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