Synthesis of 2H-pyrroles via the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides

Choong Leol Yoo, Marilyn M. Olmstead, Dean J. Tantillo, Mark J. Kurth

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

3,4-Dihydro-2H-pyrrole derivatives were synthesized by the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides. Acrylamide substitution patterns and benzimidoyl chloride equilibration were investigated.

Original languageEnglish (US)
Pages (from-to)477-481
Number of pages5
JournalTetrahedron Letters
Volume47
Issue number4
DOIs
StatePublished - Jan 23 2006

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ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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