Abstract
Sweet's syndrome-like (Sweet's-like) neutrophilic panniculitis is usually idiopathic, but is frequently associated with hematologic, inflammatory, and immunologic disease. Drug-related cases of Sweet's syndrome have been reported. Of relevance, chemotherapy with the retinoid all-trans-retinoic acid (ATRA) infrequently induces Sweet's-like neutrophilic panniculitis that occurs concomitantly with neutrophilic differentiation. The pathologic features are limited to the adipose tissue or include both the dermis and the subcutaneous fat; the neutrophilic infiltrate can be observed in the lobules, the septae, or both. We present this case because of the unusual subcutaneous neutrophilic infiltrate consistent with Sweet's-like neutrophilic lobular panniculitis in a patient with acute promyelocytic leukemia receiving ATRA chemotherapy. This case highlights the important connection between ATRA and Sweet's syndrome.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 690-693 |
| Number of pages | 4 |
| Journal | Journal of the American Academy of Dermatology |
| Volume | 56 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 2007 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Dermatology
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Sweet's syndrome-like neutrophilic lobular panniculitis associated with all-trans-retinoic acid chemotherapy in a patient with acute promyelocytic leukemia. / Jagdeo, Jared; Campbell, Ross; Long, Thomas; Muglia, Jennie; Telang, Gladys; Robinson-Bostom, Leslie.
In: Journal of the American Academy of Dermatology, Vol. 56, No. 4, 04.2007, p. 690-693.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Sweet's syndrome-like neutrophilic lobular panniculitis associated with all-trans-retinoic acid chemotherapy in a patient with acute promyelocytic leukemia
AU - Jagdeo, Jared
AU - Campbell, Ross
AU - Long, Thomas
AU - Muglia, Jennie
AU - Telang, Gladys
AU - Robinson-Bostom, Leslie
PY - 2007/4
Y1 - 2007/4
N2 - Sweet's syndrome-like (Sweet's-like) neutrophilic panniculitis is usually idiopathic, but is frequently associated with hematologic, inflammatory, and immunologic disease. Drug-related cases of Sweet's syndrome have been reported. Of relevance, chemotherapy with the retinoid all-trans-retinoic acid (ATRA) infrequently induces Sweet's-like neutrophilic panniculitis that occurs concomitantly with neutrophilic differentiation. The pathologic features are limited to the adipose tissue or include both the dermis and the subcutaneous fat; the neutrophilic infiltrate can be observed in the lobules, the septae, or both. We present this case because of the unusual subcutaneous neutrophilic infiltrate consistent with Sweet's-like neutrophilic lobular panniculitis in a patient with acute promyelocytic leukemia receiving ATRA chemotherapy. This case highlights the important connection between ATRA and Sweet's syndrome.
AB - Sweet's syndrome-like (Sweet's-like) neutrophilic panniculitis is usually idiopathic, but is frequently associated with hematologic, inflammatory, and immunologic disease. Drug-related cases of Sweet's syndrome have been reported. Of relevance, chemotherapy with the retinoid all-trans-retinoic acid (ATRA) infrequently induces Sweet's-like neutrophilic panniculitis that occurs concomitantly with neutrophilic differentiation. The pathologic features are limited to the adipose tissue or include both the dermis and the subcutaneous fat; the neutrophilic infiltrate can be observed in the lobules, the septae, or both. We present this case because of the unusual subcutaneous neutrophilic infiltrate consistent with Sweet's-like neutrophilic lobular panniculitis in a patient with acute promyelocytic leukemia receiving ATRA chemotherapy. This case highlights the important connection between ATRA and Sweet's syndrome.
UR - http://www.scopus.com/inward/record.url?scp=33947186344&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33947186344&partnerID=8YFLogxK
U2 - 10.1016/j.jaad.2006.08.011
DO - 10.1016/j.jaad.2006.08.011
M3 - Article
VL - 56
SP - 690
EP - 693
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 4
ER -