Susceptibility of European jackdaws (Corvus monedula) to experimental infection with lineage 1 and 2 West Nile viruses

Stephanie M. Lim, Aaron Brault, Geert van Amerongen, Varsha D. Sewbalaksing, Albert D.M.E. Osterhaus, Byron E.E. Martina, Penelope Koraka

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Mass bird mortality has been observed in North America after the introduction of West Nile virus (WNV), most notably massive die-offs of American crows (Corvus brachyrhynchos). In contrast, WNV epidemic activity in Europe has been characterized by very low incidences of bird mortality. As the general susceptibility of European corvids to strains of WNV remains in question, European jackdaws (Corvus monedula) were inoculated with WNV strains circulating currently in Greece (Greece-10), Italy (FIN and Ita09) and Hungary (578/10), as well as a North American (NY99) genotype with a demonstrated corvid virulence phenotype. Infection with all strains except WNV-FIN resulted in mortality. Viraemia was observed for birds inoculated with all strains and virus was detected in a series of organs upon necropsy. These results suggested that jackdaws could potentially function as a sentinel for following WNV transmission in Europe; however, elicited viraemia levels might be too low to allow for efficient transmission of virus to mosquitoes.

Original languageEnglish (US)
Pages (from-to)1320-1329
Number of pages10
JournalJournal of General Virology
Volume95
Issue numberPART 6
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

ASJC Scopus subject areas

  • Virology

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    Lim, S. M., Brault, A., van Amerongen, G., Sewbalaksing, V. D., Osterhaus, A. D. M. E., Martina, B. E. E., & Koraka, P. (2014). Susceptibility of European jackdaws (Corvus monedula) to experimental infection with lineage 1 and 2 West Nile viruses. Journal of General Virology, 95(PART 6), 1320-1329. https://doi.org/10.1099/vir.0.063651-0