Abstract
Cattle bloods containing only polymerase chain reaction (PCR)-detectable bluetongue-10 viral nucleic acid, but as determined by virus isolation techniques, not bluetongue-10 virus, were incapable of infecting intrathoracically inoculated Culicoides variipennis sonorensis. These insects also failed to transmit bluetongue-10 virus when fed on sheep. Cattle whose blood contain only PCR-detectable bluetongue viral nucleic acid, but no infectious virus, are unlikely to play a role in the epidemiology of bluetongue. The biological significance of PCR-based detection assays and their effect on animal health regulations on the international trade of livestock and livestock germplasm is discussed. Bluetongue virus infection provides a very useful model with which to study arthropod-transmitted RNA virus infections of humans and other animals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 481-485 |
| Number of pages | 5 |
| Journal | American Journal of Tropical Medicine and Hygiene |
| Volume | 54 |
| Issue number | 5 |
| State | Published - May 1996 |
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ASJC Scopus subject areas
- Parasitology
- Infectious Diseases
Cite this
Susceptibility of Culicoides variipennis sonorensis to infection by polymerase chain reaction-detectable bluetongue virus in cattle blood. / Tabachnick, Walter J.; Maclachlan, Nigel J; Thompson, Lee H.; Hunt, Gregg J.; Patton, John F.
In: American Journal of Tropical Medicine and Hygiene, Vol. 54, No. 5, 05.1996, p. 481-485.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Susceptibility of Culicoides variipennis sonorensis to infection by polymerase chain reaction-detectable bluetongue virus in cattle blood
AU - Tabachnick, Walter J.
AU - Maclachlan, Nigel J
AU - Thompson, Lee H.
AU - Hunt, Gregg J.
AU - Patton, John F.
PY - 1996/5
Y1 - 1996/5
N2 - Cattle bloods containing only polymerase chain reaction (PCR)-detectable bluetongue-10 viral nucleic acid, but as determined by virus isolation techniques, not bluetongue-10 virus, were incapable of infecting intrathoracically inoculated Culicoides variipennis sonorensis. These insects also failed to transmit bluetongue-10 virus when fed on sheep. Cattle whose blood contain only PCR-detectable bluetongue viral nucleic acid, but no infectious virus, are unlikely to play a role in the epidemiology of bluetongue. The biological significance of PCR-based detection assays and their effect on animal health regulations on the international trade of livestock and livestock germplasm is discussed. Bluetongue virus infection provides a very useful model with which to study arthropod-transmitted RNA virus infections of humans and other animals.
AB - Cattle bloods containing only polymerase chain reaction (PCR)-detectable bluetongue-10 viral nucleic acid, but as determined by virus isolation techniques, not bluetongue-10 virus, were incapable of infecting intrathoracically inoculated Culicoides variipennis sonorensis. These insects also failed to transmit bluetongue-10 virus when fed on sheep. Cattle whose blood contain only PCR-detectable bluetongue viral nucleic acid, but no infectious virus, are unlikely to play a role in the epidemiology of bluetongue. The biological significance of PCR-based detection assays and their effect on animal health regulations on the international trade of livestock and livestock germplasm is discussed. Bluetongue virus infection provides a very useful model with which to study arthropod-transmitted RNA virus infections of humans and other animals.
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UR - http://www.scopus.com/inward/citedby.url?scp=0029894193&partnerID=8YFLogxK
M3 - Article
C2 - 8644902
AN - SCOPUS:0029894193
VL - 54
SP - 481
EP - 485
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
SN - 0002-9637
IS - 5
ER -