Abstract
Cattle bloods containing only polymerase chain reaction (PCR)-detectable bluetongue-10 viral nucleic acid, but as determined by virus isolation techniques, not bluetongue-10 virus, were incapable of infecting intrathoracically inoculated Culicoides variipennis sonorensis. These insects also failed to transmit bluetongue-10 virus when fed on sheep. Cattle whose blood contain only PCR-detectable bluetongue viral nucleic acid, but no infectious virus, are unlikely to play a role in the epidemiology of bluetongue. The biological significance of PCR-based detection assays and their effect on animal health regulations on the international trade of livestock and livestock germplasm is discussed. Bluetongue virus infection provides a very useful model with which to study arthropod-transmitted RNA virus infections of humans and other animals.
Original language | English (US) |
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Pages (from-to) | 481-485 |
Number of pages | 5 |
Journal | American Journal of Tropical Medicine and Hygiene |
Volume | 54 |
Issue number | 5 |
State | Published - May 1996 |
ASJC Scopus subject areas
- Parasitology
- Infectious Diseases