Susceptibility of Chinese rhesus monkeys to SIV infection

Tricia H. Burdo, Maria Cecilia G. Marcondes, Caroline M.S. Lanigan, Cecilia Penedo, Howard S. Fox

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

The use of China-derived monkeys in AIDS research has been limited by reports of reduced susceptibility to SIV. We performed a serial passage of SIV in Chinese macaques, which resulted in a viral stock capable of inducing simian AIDS and high levels of replication in these animals. Similar to HIV in humans, SIV pathogenesis in non-human primates is not limited by geographical origin. Chinese macaques are useful in pathogenesis, vaccine, and therapeutic studies in AIDS.

Original languageEnglish (US)
Pages (from-to)1704-1706
Number of pages3
JournalAIDS
Volume19
Issue number15
DOIs
StatePublished - Oct 14 2005

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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  • Cite this

    Burdo, T. H., Marcondes, M. C. G., Lanigan, C. M. S., Penedo, C., & Fox, H. S. (2005). Susceptibility of Chinese rhesus monkeys to SIV infection. AIDS, 19(15), 1704-1706. https://doi.org/10.1097/01.aids.0000186823.76230.33