Susceptibility of Chinese rhesus monkeys to SIV infection

Tricia H. Burdo, Maria Cecilia G. Marcondes, Caroline M.S. Lanigan, Cecilia Penedo, Howard S. Fox

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

The use of China-derived monkeys in AIDS research has been limited by reports of reduced susceptibility to SIV. We performed a serial passage of SIV in Chinese macaques, which resulted in a viral stock capable of inducing simian AIDS and high levels of replication in these animals. Similar to HIV in humans, SIV pathogenesis in non-human primates is not limited by geographical origin. Chinese macaques are useful in pathogenesis, vaccine, and therapeutic studies in AIDS.

Original languageEnglish (US)
Pages (from-to)1704-1706
Number of pages3
JournalAIDS
Volume19
Issue number15
DOIs
StatePublished - Oct 14 2005

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Macaca
Macaca mulatta
Simian Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
Serial Passage
Infection
Primates
Haplorhini
China
Vaccines
HIV
Research
Therapeutics

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

Cite this

Burdo, T. H., Marcondes, M. C. G., Lanigan, C. M. S., Penedo, C., & Fox, H. S. (2005). Susceptibility of Chinese rhesus monkeys to SIV infection. AIDS, 19(15), 1704-1706. https://doi.org/10.1097/01.aids.0000186823.76230.33

Susceptibility of Chinese rhesus monkeys to SIV infection. / Burdo, Tricia H.; Marcondes, Maria Cecilia G.; Lanigan, Caroline M.S.; Penedo, Cecilia; Fox, Howard S.

In: AIDS, Vol. 19, No. 15, 14.10.2005, p. 1704-1706.

Research output: Contribution to journalArticle

Burdo, TH, Marcondes, MCG, Lanigan, CMS, Penedo, C & Fox, HS 2005, 'Susceptibility of Chinese rhesus monkeys to SIV infection', AIDS, vol. 19, no. 15, pp. 1704-1706. https://doi.org/10.1097/01.aids.0000186823.76230.33
Burdo, Tricia H. ; Marcondes, Maria Cecilia G. ; Lanigan, Caroline M.S. ; Penedo, Cecilia ; Fox, Howard S. / Susceptibility of Chinese rhesus monkeys to SIV infection. In: AIDS. 2005 ; Vol. 19, No. 15. pp. 1704-1706.
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