Susceptibility of carrion crows to experimental infection with lineage 1 and 2 West Nile viruses

Stephanie M. Lim, Aaron Brault, Geert van Amerongen, Angela M. Bosco-Lauth, Hannah Romo, Varsha D. Sewbalaksing, Richard A. Bowen, Albert D.M.E. Osterhaus, Penelope Koraka, Byron E.E. Martina

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

West Nile virus (WNV) outbreaks in North America have been characterized by substantial die-offs of American crows (Corvus brachyrhynchos). In contrast, a low incidence of bird deaths has been observed during WNV epidemic activity in Europe. To examine the susceptibility of the western European counterpart of American crows, we inoculated carrion crows (Corvus corone) with WNV strains isolated in Greece (Gr-10), Italy (FIN and Ita09), and Hungary (578/10) and with the highly virulent North American genotype strain (NY99). We also inoculated American crows with a selection of these strains to examine the strains’ virulence in a highly susceptible bird species. Infection with all strains, except WNV FIN, resulted in high rates of death and high-level viremia in both bird species and virus dissemination to several organs. These results suggest that carrion crows are highly susceptible to WNV and may potentially be useful as part of dead bird surveillance for early warning of WNV activity in Europe.

Original languageEnglish (US)
Pages (from-to)1357-1365
Number of pages9
JournalEmerging Infectious Diseases
Volume21
Issue number8
DOIs
StatePublished - Jul 23 2015
Externally publishedYes

Fingerprint

Crows
West Nile virus
Birds
Infection
Hungary
Viremia
Greece
North America
Italy
Disease Outbreaks
Virulence
Genotype
Viruses
Mortality
Incidence

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Lim, S. M., Brault, A., van Amerongen, G., Bosco-Lauth, A. M., Romo, H., Sewbalaksing, V. D., ... Martina, B. E. E. (2015). Susceptibility of carrion crows to experimental infection with lineage 1 and 2 West Nile viruses. Emerging Infectious Diseases, 21(8), 1357-1365. https://doi.org/10.3201/eid2108.140714

Susceptibility of carrion crows to experimental infection with lineage 1 and 2 West Nile viruses. / Lim, Stephanie M.; Brault, Aaron; van Amerongen, Geert; Bosco-Lauth, Angela M.; Romo, Hannah; Sewbalaksing, Varsha D.; Bowen, Richard A.; Osterhaus, Albert D.M.E.; Koraka, Penelope; Martina, Byron E.E.

In: Emerging Infectious Diseases, Vol. 21, No. 8, 23.07.2015, p. 1357-1365.

Research output: Contribution to journalArticle

Lim, SM, Brault, A, van Amerongen, G, Bosco-Lauth, AM, Romo, H, Sewbalaksing, VD, Bowen, RA, Osterhaus, ADME, Koraka, P & Martina, BEE 2015, 'Susceptibility of carrion crows to experimental infection with lineage 1 and 2 West Nile viruses', Emerging Infectious Diseases, vol. 21, no. 8, pp. 1357-1365. https://doi.org/10.3201/eid2108.140714
Lim, Stephanie M. ; Brault, Aaron ; van Amerongen, Geert ; Bosco-Lauth, Angela M. ; Romo, Hannah ; Sewbalaksing, Varsha D. ; Bowen, Richard A. ; Osterhaus, Albert D.M.E. ; Koraka, Penelope ; Martina, Byron E.E. / Susceptibility of carrion crows to experimental infection with lineage 1 and 2 West Nile viruses. In: Emerging Infectious Diseases. 2015 ; Vol. 21, No. 8. pp. 1357-1365.
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