Survival analysis of dogs diagnosed with canine peritoneal larval cestodiasis (Mesocestoides spp.)

Walter M Boyce, Lisa Shender, Laura Schultz, Winston Vickers, Christine K Johnson, Michael H Ziccardi, Laurel A Beckett, Kerry Padgett, Paul Crosbie, Jane E Sykes

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Canine peritoneal larval cestodiasis (CPLC) is a poorly understood disease of dogs caused by asexual multiplication of larval Mesocestoides spp. tapeworms. In this study, we examined the descriptive statistics and survival characteristics of 60 dogs diagnosed with CPLC from 1989 to 2009. Clinically affected dogs presented with ascites (60%), anorexia/weight loss (42%), vomiting (23%), diarrhea (9%) and tachypnea (9%), while subclinical infections (22%) were incidentally detected, typically during ovariohysterectomy or neuter. Survival at 6 months and 1 year post-diagnosis were 72.3% and 60.5%, respectively, and survival was not affected by sex or age. Using Cox proportional hazard analyses, we determined that the most significant factors influencing survival were the severity of clinical signs at the time of diagnosis and application of an aggressive treatment strategy after diagnosis. Dogs that were not treated aggressively were >5 times more likely to die than dogs that were treated with a combination of surgery/lavage and high doses of fenbendazole.

Original languageEnglish (US)
Pages (from-to)256-261
Number of pages6
JournalVeterinary Parasitology
Volume180
Issue number3-4
DOIs
StatePublished - Aug 25 2011

Fingerprint

Mesocestoides
Survival Analysis
Canidae
Dogs
dogs
Fenbendazole
Dog Diseases
Tachypnea
Asymptomatic Infections
Cestoda
Therapeutic Irrigation
Anorexia
Ascites
Vomiting
Weight Loss
Diarrhea
fenbendazole
spaying
tapeworms
dog diseases

Keywords

  • Canine
  • Cestode
  • Mesocestoides
  • Survival
  • Tapeworm

ASJC Scopus subject areas

  • Parasitology
  • veterinary(all)

Cite this

Survival analysis of dogs diagnosed with canine peritoneal larval cestodiasis (Mesocestoides spp.). / Boyce, Walter M; Shender, Lisa; Schultz, Laura; Vickers, Winston; Johnson, Christine K; Ziccardi, Michael H; Beckett, Laurel A; Padgett, Kerry; Crosbie, Paul; Sykes, Jane E.

In: Veterinary Parasitology, Vol. 180, No. 3-4, 25.08.2011, p. 256-261.

Research output: Contribution to journalArticle

@article{70fc0875da3a4cc08751727a73c7f22d,
title = "Survival analysis of dogs diagnosed with canine peritoneal larval cestodiasis (Mesocestoides spp.)",
abstract = "Canine peritoneal larval cestodiasis (CPLC) is a poorly understood disease of dogs caused by asexual multiplication of larval Mesocestoides spp. tapeworms. In this study, we examined the descriptive statistics and survival characteristics of 60 dogs diagnosed with CPLC from 1989 to 2009. Clinically affected dogs presented with ascites (60{\%}), anorexia/weight loss (42{\%}), vomiting (23{\%}), diarrhea (9{\%}) and tachypnea (9{\%}), while subclinical infections (22{\%}) were incidentally detected, typically during ovariohysterectomy or neuter. Survival at 6 months and 1 year post-diagnosis were 72.3{\%} and 60.5{\%}, respectively, and survival was not affected by sex or age. Using Cox proportional hazard analyses, we determined that the most significant factors influencing survival were the severity of clinical signs at the time of diagnosis and application of an aggressive treatment strategy after diagnosis. Dogs that were not treated aggressively were >5 times more likely to die than dogs that were treated with a combination of surgery/lavage and high doses of fenbendazole.",
keywords = "Canine, Cestode, Mesocestoides, Survival, Tapeworm",
author = "Boyce, {Walter M} and Lisa Shender and Laura Schultz and Winston Vickers and Johnson, {Christine K} and Ziccardi, {Michael H} and Beckett, {Laurel A} and Kerry Padgett and Paul Crosbie and Sykes, {Jane E}",
year = "2011",
month = "8",
day = "25",
doi = "10.1016/j.vetpar.2011.03.023",
language = "English (US)",
volume = "180",
pages = "256--261",
journal = "Veterinary Parasitology: Regional Studies and Reports",
issn = "0304-4017",
publisher = "Elsevier",
number = "3-4",

}

TY - JOUR

T1 - Survival analysis of dogs diagnosed with canine peritoneal larval cestodiasis (Mesocestoides spp.)

AU - Boyce, Walter M

AU - Shender, Lisa

AU - Schultz, Laura

AU - Vickers, Winston

AU - Johnson, Christine K

AU - Ziccardi, Michael H

AU - Beckett, Laurel A

AU - Padgett, Kerry

AU - Crosbie, Paul

AU - Sykes, Jane E

PY - 2011/8/25

Y1 - 2011/8/25

N2 - Canine peritoneal larval cestodiasis (CPLC) is a poorly understood disease of dogs caused by asexual multiplication of larval Mesocestoides spp. tapeworms. In this study, we examined the descriptive statistics and survival characteristics of 60 dogs diagnosed with CPLC from 1989 to 2009. Clinically affected dogs presented with ascites (60%), anorexia/weight loss (42%), vomiting (23%), diarrhea (9%) and tachypnea (9%), while subclinical infections (22%) were incidentally detected, typically during ovariohysterectomy or neuter. Survival at 6 months and 1 year post-diagnosis were 72.3% and 60.5%, respectively, and survival was not affected by sex or age. Using Cox proportional hazard analyses, we determined that the most significant factors influencing survival were the severity of clinical signs at the time of diagnosis and application of an aggressive treatment strategy after diagnosis. Dogs that were not treated aggressively were >5 times more likely to die than dogs that were treated with a combination of surgery/lavage and high doses of fenbendazole.

AB - Canine peritoneal larval cestodiasis (CPLC) is a poorly understood disease of dogs caused by asexual multiplication of larval Mesocestoides spp. tapeworms. In this study, we examined the descriptive statistics and survival characteristics of 60 dogs diagnosed with CPLC from 1989 to 2009. Clinically affected dogs presented with ascites (60%), anorexia/weight loss (42%), vomiting (23%), diarrhea (9%) and tachypnea (9%), while subclinical infections (22%) were incidentally detected, typically during ovariohysterectomy or neuter. Survival at 6 months and 1 year post-diagnosis were 72.3% and 60.5%, respectively, and survival was not affected by sex or age. Using Cox proportional hazard analyses, we determined that the most significant factors influencing survival were the severity of clinical signs at the time of diagnosis and application of an aggressive treatment strategy after diagnosis. Dogs that were not treated aggressively were >5 times more likely to die than dogs that were treated with a combination of surgery/lavage and high doses of fenbendazole.

KW - Canine

KW - Cestode

KW - Mesocestoides

KW - Survival

KW - Tapeworm

UR - http://www.scopus.com/inward/record.url?scp=79960834547&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960834547&partnerID=8YFLogxK

U2 - 10.1016/j.vetpar.2011.03.023

DO - 10.1016/j.vetpar.2011.03.023

M3 - Article

C2 - 21497443

AN - SCOPUS:79960834547

VL - 180

SP - 256

EP - 261

JO - Veterinary Parasitology: Regional Studies and Reports

JF - Veterinary Parasitology: Regional Studies and Reports

SN - 0304-4017

IS - 3-4

ER -