Survey on newly characterized iron uptake systems of Yersinia enterocolitica.

Andreas J Baumler, R. Koebnik, I. Stojiljkovic, J. Heesemann, V. Braun, K. Hantke

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Iron assimilation systems have been shown to be important for virulence in Yersinia enterocolitica. In principle, iron transport in Y. enterocolitica is similarly organized as in Escherichia coli although some differences exist in the siderophores used. A TonB function was identified which in a tonB mutant was complemented by the E. coli tonB gene. Three outer membrane receptors for siderophores were cloned and sequenced: FoxA for ferrioxamine B and E, FcuA for ferrichrome and HemR for heme uptake. In addition, two receptors were identified by mutants: CccA for catechol cephalosporins and FyuA for yersiniabactin, the siderophore produced by virulent yersiniae. In addition, the FyuA protein is assumed to be the pesticin receptor.

Original languageEnglish (US)
Pages (from-to)416-424
Number of pages9
JournalZentralblatt fur Bakteriologie : international journal of medical microbiology
Volume278
Issue number2-3
StatePublished - Apr 1993
Externally publishedYes

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Siderophores
Yersinia enterocolitica
Ferrichrome
Iron
Escherichia coli
Yersinia
Cephalosporins
Heme
Virulence
Genes
Proteins
Surveys and Questionnaires
siderophore receptors
ferrioxamine E
catechol
ferrioxamine B
yersiniabactin
Pesticin

ASJC Scopus subject areas

  • Immunology

Cite this

Survey on newly characterized iron uptake systems of Yersinia enterocolitica. / Baumler, Andreas J; Koebnik, R.; Stojiljkovic, I.; Heesemann, J.; Braun, V.; Hantke, K.

In: Zentralblatt fur Bakteriologie : international journal of medical microbiology, Vol. 278, No. 2-3, 04.1993, p. 416-424.

Research output: Contribution to journalArticle

Baumler, Andreas J ; Koebnik, R. ; Stojiljkovic, I. ; Heesemann, J. ; Braun, V. ; Hantke, K. / Survey on newly characterized iron uptake systems of Yersinia enterocolitica. In: Zentralblatt fur Bakteriologie : international journal of medical microbiology. 1993 ; Vol. 278, No. 2-3. pp. 416-424.
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