Surgical risk factors for post-operative pneumonia following meningioma resection

Taemin Oh, Michael Safaee, Matthew Z. Sun, Roxanna M. Garcia, Michael W. McDermott, Andrew T. Parsa, Orin Bloch

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective Post-operative pneumonia (PNA) is a significant cause of surgically associated morbidity and mortality. We aimed to identify intraoperative factors during meningioma surgery that were associated with a high risk of post-operative PNA to risk-stratify patients and improve outcomes. Methods We conducted an institutional retrospective review on all patients who underwent craniotomies for meningioma between 2009 and 2012. Using medical records, we extracted patient demographics, tumor characteristics, tumor pathology, surgical positioning, procedure duration, estimated blood loss (EBL), and the occurrence of post-operative PNA. Results In our series, 464 patients underwent craniotomy for meningioma. There was a female predominance (331 women, 133 men), with mean age of 58 ± 13 years (range 18-92). There were 354 grade I, 79 grade II, and 30 grade III tumors. Overall, 1.3% of patients developed PNA. Patient age (p = 0.01), procedure duration (p < 0.01), and blood loss (p = 0.02) were associated with increased incidence of PNA. The development of post-operative PNA resulted in a significantly increased duration of hospital stay (19 ± 7 vs. 7 ± 7 days, p = 0.00). In multivariate analysis, patient age (OR = 1.13, CI: 1.04-1.22; p = 0.004), EBL (OR = 1.01, CI: 1.00-1.02; p = 0.023), and procedure duration (OR = 1.06, CI: 1.01-1.11; p = 0.012) were significant predictors of development of PNA. Conclusions Patient age and procedure duration are significantly associated with post-operative PNA following meningioma resection, which results in prolonged hospitalization. Efforts to minimize operative times and EBL, especially in the elderly, may reduce PNA rates and hospitalization time.

Original languageEnglish (US)
Pages (from-to)76-79
Number of pages4
JournalClinical Neurology and Neurosurgery
Volume118
DOIs
StatePublished - Mar 1 2014
Externally publishedYes

Fingerprint

Meningioma
Pneumonia
Craniotomy
Hospitalization
Neoplasms
Surgical Pathology
Operative Time
Medical Records
Length of Stay
Multivariate Analysis
Demography
Morbidity
Mortality
Incidence

Keywords

  • Complications
  • Meningioma
  • Morbidity
  • Pneumonia
  • Surgery

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Surgical risk factors for post-operative pneumonia following meningioma resection. / Oh, Taemin; Safaee, Michael; Sun, Matthew Z.; Garcia, Roxanna M.; McDermott, Michael W.; Parsa, Andrew T.; Bloch, Orin.

In: Clinical Neurology and Neurosurgery, Vol. 118, 01.03.2014, p. 76-79.

Research output: Contribution to journalArticle

Oh, Taemin ; Safaee, Michael ; Sun, Matthew Z. ; Garcia, Roxanna M. ; McDermott, Michael W. ; Parsa, Andrew T. ; Bloch, Orin. / Surgical risk factors for post-operative pneumonia following meningioma resection. In: Clinical Neurology and Neurosurgery. 2014 ; Vol. 118. pp. 76-79.
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abstract = "Objective Post-operative pneumonia (PNA) is a significant cause of surgically associated morbidity and mortality. We aimed to identify intraoperative factors during meningioma surgery that were associated with a high risk of post-operative PNA to risk-stratify patients and improve outcomes. Methods We conducted an institutional retrospective review on all patients who underwent craniotomies for meningioma between 2009 and 2012. Using medical records, we extracted patient demographics, tumor characteristics, tumor pathology, surgical positioning, procedure duration, estimated blood loss (EBL), and the occurrence of post-operative PNA. Results In our series, 464 patients underwent craniotomy for meningioma. There was a female predominance (331 women, 133 men), with mean age of 58 ± 13 years (range 18-92). There were 354 grade I, 79 grade II, and 30 grade III tumors. Overall, 1.3{\%} of patients developed PNA. Patient age (p = 0.01), procedure duration (p < 0.01), and blood loss (p = 0.02) were associated with increased incidence of PNA. The development of post-operative PNA resulted in a significantly increased duration of hospital stay (19 ± 7 vs. 7 ± 7 days, p = 0.00). In multivariate analysis, patient age (OR = 1.13, CI: 1.04-1.22; p = 0.004), EBL (OR = 1.01, CI: 1.00-1.02; p = 0.023), and procedure duration (OR = 1.06, CI: 1.01-1.11; p = 0.012) were significant predictors of development of PNA. Conclusions Patient age and procedure duration are significantly associated with post-operative PNA following meningioma resection, which results in prolonged hospitalization. Efforts to minimize operative times and EBL, especially in the elderly, may reduce PNA rates and hospitalization time.",
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T1 - Surgical risk factors for post-operative pneumonia following meningioma resection

AU - Oh, Taemin

AU - Safaee, Michael

AU - Sun, Matthew Z.

AU - Garcia, Roxanna M.

AU - McDermott, Michael W.

AU - Parsa, Andrew T.

AU - Bloch, Orin

PY - 2014/3/1

Y1 - 2014/3/1

N2 - Objective Post-operative pneumonia (PNA) is a significant cause of surgically associated morbidity and mortality. We aimed to identify intraoperative factors during meningioma surgery that were associated with a high risk of post-operative PNA to risk-stratify patients and improve outcomes. Methods We conducted an institutional retrospective review on all patients who underwent craniotomies for meningioma between 2009 and 2012. Using medical records, we extracted patient demographics, tumor characteristics, tumor pathology, surgical positioning, procedure duration, estimated blood loss (EBL), and the occurrence of post-operative PNA. Results In our series, 464 patients underwent craniotomy for meningioma. There was a female predominance (331 women, 133 men), with mean age of 58 ± 13 years (range 18-92). There were 354 grade I, 79 grade II, and 30 grade III tumors. Overall, 1.3% of patients developed PNA. Patient age (p = 0.01), procedure duration (p < 0.01), and blood loss (p = 0.02) were associated with increased incidence of PNA. The development of post-operative PNA resulted in a significantly increased duration of hospital stay (19 ± 7 vs. 7 ± 7 days, p = 0.00). In multivariate analysis, patient age (OR = 1.13, CI: 1.04-1.22; p = 0.004), EBL (OR = 1.01, CI: 1.00-1.02; p = 0.023), and procedure duration (OR = 1.06, CI: 1.01-1.11; p = 0.012) were significant predictors of development of PNA. Conclusions Patient age and procedure duration are significantly associated with post-operative PNA following meningioma resection, which results in prolonged hospitalization. Efforts to minimize operative times and EBL, especially in the elderly, may reduce PNA rates and hospitalization time.

AB - Objective Post-operative pneumonia (PNA) is a significant cause of surgically associated morbidity and mortality. We aimed to identify intraoperative factors during meningioma surgery that were associated with a high risk of post-operative PNA to risk-stratify patients and improve outcomes. Methods We conducted an institutional retrospective review on all patients who underwent craniotomies for meningioma between 2009 and 2012. Using medical records, we extracted patient demographics, tumor characteristics, tumor pathology, surgical positioning, procedure duration, estimated blood loss (EBL), and the occurrence of post-operative PNA. Results In our series, 464 patients underwent craniotomy for meningioma. There was a female predominance (331 women, 133 men), with mean age of 58 ± 13 years (range 18-92). There were 354 grade I, 79 grade II, and 30 grade III tumors. Overall, 1.3% of patients developed PNA. Patient age (p = 0.01), procedure duration (p < 0.01), and blood loss (p = 0.02) were associated with increased incidence of PNA. The development of post-operative PNA resulted in a significantly increased duration of hospital stay (19 ± 7 vs. 7 ± 7 days, p = 0.00). In multivariate analysis, patient age (OR = 1.13, CI: 1.04-1.22; p = 0.004), EBL (OR = 1.01, CI: 1.00-1.02; p = 0.023), and procedure duration (OR = 1.06, CI: 1.01-1.11; p = 0.012) were significant predictors of development of PNA. Conclusions Patient age and procedure duration are significantly associated with post-operative PNA following meningioma resection, which results in prolonged hospitalization. Efforts to minimize operative times and EBL, especially in the elderly, may reduce PNA rates and hospitalization time.

KW - Complications

KW - Meningioma

KW - Morbidity

KW - Pneumonia

KW - Surgery

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