Abstract
Clinical and cardiac catheterization data were collected from 39 infants with coarctation of the aorta and ventricular septal defect, 31 of whom were initially managed only by surgical repair of coarctation. Data were analyzed to determine mortality, morbidity, outcome and factors that might predict survival or the need for septal defect closure. Of the eight patients who did not require surgical treatment before 3 months of age, seven underwent coarctation repair alone at a mean age of 2.3 years. Of the 23 infants managed with coarctation repair alone, before age 3 months, 9 needed no additional surgical treatment and 6 required early and 8 required late repair of the ventricular septal defect. Seven infants underwent coarctation repair and simultaneous pulmonary artery bandnig and one eventually required debanding after spontaneous closure of the septal defect. The overall mortality rate in this series was 10.3% (mean follow-up time 5.7 years). Of 39 infants, 16 (41%) never required a second operation for ventricular septal defect closure. For patients who had only coarclation or coarctation repair with pulmonary artery banding at <3 months of age, ventricular septal defect size was categorized as small (<0.5 cm/m2), moderate (<1 cm/m2) or large (>1 cm/m2) on the basis of defect size at operative repair or echocardiographic or angiographic assessment. Defect size did not necessarily correlate with the need for operative repair. Stepwise multiple regression analysis revealed that increased right to left ventricular peak systolic pressure (p = 0.004) and decreased systemic venous oxygen content (p = 0.028) were significantly predictive of the eventual need for ventricular septal defect repair. Thus, most infants with coarctation of the aorta and ventricular septal defect do not require pulmonary artery banding or open heart closure of the ventricular septal defect at the time of coarctation repair. A significant number of infants will not require a second operation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 176-180 |
| Number of pages | 5 |
| Journal | Journal of the American College of Cardiology |
| Volume | 20 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1992 |
| Externally published | Yes |
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Surgical management of the infant with coarctation of the aorta and ventricular septal defect. / Park, Jeanny K; Dell, Ralph B.; Ellis, Kent; Gersony, Welton M.
In: Journal of the American College of Cardiology, Vol. 20, No. 1, 1992, p. 176-180.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Surgical management of the infant with coarctation of the aorta and ventricular septal defect
AU - Park, Jeanny K
AU - Dell, Ralph B.
AU - Ellis, Kent
AU - Gersony, Welton M.
PY - 1992
Y1 - 1992
N2 - Clinical and cardiac catheterization data were collected from 39 infants with coarctation of the aorta and ventricular septal defect, 31 of whom were initially managed only by surgical repair of coarctation. Data were analyzed to determine mortality, morbidity, outcome and factors that might predict survival or the need for septal defect closure. Of the eight patients who did not require surgical treatment before 3 months of age, seven underwent coarctation repair alone at a mean age of 2.3 years. Of the 23 infants managed with coarctation repair alone, before age 3 months, 9 needed no additional surgical treatment and 6 required early and 8 required late repair of the ventricular septal defect. Seven infants underwent coarctation repair and simultaneous pulmonary artery bandnig and one eventually required debanding after spontaneous closure of the septal defect. The overall mortality rate in this series was 10.3% (mean follow-up time 5.7 years). Of 39 infants, 16 (41%) never required a second operation for ventricular septal defect closure. For patients who had only coarclation or coarctation repair with pulmonary artery banding at <3 months of age, ventricular septal defect size was categorized as small (<0.5 cm/m2), moderate (<1 cm/m2) or large (>1 cm/m2) on the basis of defect size at operative repair or echocardiographic or angiographic assessment. Defect size did not necessarily correlate with the need for operative repair. Stepwise multiple regression analysis revealed that increased right to left ventricular peak systolic pressure (p = 0.004) and decreased systemic venous oxygen content (p = 0.028) were significantly predictive of the eventual need for ventricular septal defect repair. Thus, most infants with coarctation of the aorta and ventricular septal defect do not require pulmonary artery banding or open heart closure of the ventricular septal defect at the time of coarctation repair. A significant number of infants will not require a second operation.
AB - Clinical and cardiac catheterization data were collected from 39 infants with coarctation of the aorta and ventricular septal defect, 31 of whom were initially managed only by surgical repair of coarctation. Data were analyzed to determine mortality, morbidity, outcome and factors that might predict survival or the need for septal defect closure. Of the eight patients who did not require surgical treatment before 3 months of age, seven underwent coarctation repair alone at a mean age of 2.3 years. Of the 23 infants managed with coarctation repair alone, before age 3 months, 9 needed no additional surgical treatment and 6 required early and 8 required late repair of the ventricular septal defect. Seven infants underwent coarctation repair and simultaneous pulmonary artery bandnig and one eventually required debanding after spontaneous closure of the septal defect. The overall mortality rate in this series was 10.3% (mean follow-up time 5.7 years). Of 39 infants, 16 (41%) never required a second operation for ventricular septal defect closure. For patients who had only coarclation or coarctation repair with pulmonary artery banding at <3 months of age, ventricular septal defect size was categorized as small (<0.5 cm/m2), moderate (<1 cm/m2) or large (>1 cm/m2) on the basis of defect size at operative repair or echocardiographic or angiographic assessment. Defect size did not necessarily correlate with the need for operative repair. Stepwise multiple regression analysis revealed that increased right to left ventricular peak systolic pressure (p = 0.004) and decreased systemic venous oxygen content (p = 0.028) were significantly predictive of the eventual need for ventricular septal defect repair. Thus, most infants with coarctation of the aorta and ventricular septal defect do not require pulmonary artery banding or open heart closure of the ventricular septal defect at the time of coarctation repair. A significant number of infants will not require a second operation.
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UR - http://www.scopus.com/inward/citedby.url?scp=0026718309&partnerID=8YFLogxK
U2 - 10.1016/0735-1097(92)90156-H
DO - 10.1016/0735-1097(92)90156-H
M3 - Article
VL - 20
SP - 176
EP - 180
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
SN - 0735-1097
IS - 1
ER -