Surflan™ and oryzalin impair reproduction in the teleost medaka (Oryzias latipes)

L. C. Hall, M. Okihiro, M. L. Johnson, Swee J Teh

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We conducted studies to determine if the xenoestrogens Surflan™ and its active ingredient oryzalin, affect indices of reproductive fitness in medaka (Oryzias latipes). Oryzalin (0.5, 0.25 mg/l) or Surflan™ (2.0 μl/l) and oryzalin (0.5 mg/l) significantly increased the mean number of non-fertilized eggs produced by treated females paired with untreated males, or by untreated females paired with treated males. Oryzalin (1.0, 0.5, 0.25 mg/l) and Surflan™ (3.8, 2.0, 1.0 μl/l) significantly affected the time to hatch of eggs from treated females paired with untreated males, and from untreated females paired with treated males. Surflan™ (3.8, 2.0, 1.0 μl/l) induced intersex lesions in 80-100% of males. Oryzalin-exposed males exhibited a significant increase in the incidence of necrotic spermatids and necrotic spermatogonia, while oryzalin-exposed females had significantly fewer immature oocytes and an increase in the occurrence of hyperplastic ovaries. Our results indicate that Surflan™ and oryzalin affect both reproduction and gonadal histology in male and female medaka.

Original languageEnglish (US)
Pages (from-to)115-131
Number of pages17
JournalMarine Environmental Research
Volume63
Issue number2
DOIs
StatePublished - Mar 2007

Fingerprint

oryzalin
Hatches
Oryzias latipes
Histology
teleost
xenoestrogens
egg
intersex
spermatogonia
spermatids
histology
active ingredients
lesion
oocytes
fitness
immatures
incidence

Keywords

  • Ecotoxicology
  • Endocrine-disruptor
  • Herbicides
  • Medaka
  • Oryzalin
  • Surflan
  • Toxicity

ASJC Scopus subject areas

  • Aquatic Science
  • Oceanography
  • Environmental Science(all)

Cite this

Surflan™ and oryzalin impair reproduction in the teleost medaka (Oryzias latipes). / Hall, L. C.; Okihiro, M.; Johnson, M. L.; Teh, Swee J.

In: Marine Environmental Research, Vol. 63, No. 2, 03.2007, p. 115-131.

Research output: Contribution to journalArticle

Hall, L. C. ; Okihiro, M. ; Johnson, M. L. ; Teh, Swee J. / Surflan™ and oryzalin impair reproduction in the teleost medaka (Oryzias latipes). In: Marine Environmental Research. 2007 ; Vol. 63, No. 2. pp. 115-131.
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