Surface-based modeling of white matter fasciculi with orientation encoding

Hui Zhang, Paul A. Yushkevich, Tony J Simon, James C. Gee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

In this paper, we describe a novel technique for modeling sheet-like white matter (WM) fasciculi using continuous medial representation (cm-rep). In the cm-rep framework, the skeleton of a fasciculus is described by a parametric surface patch. This modeling scheme is particularly appropriate for sheet-like structures, because the shapes of such objects can be effectively captured by their skeletons. We show that dimensionality reduction can be achieved without much loss of spatial specificity by projecting data along the "less interesting" thickness direction onto the skeletons. We demonstrate that local fiber orientation of the modeled fasciculi can be encoded in our framework and show how this information can be leveraged for deriving and analyzing brain connectivity patterns on the skeleton themselves.

Original languageEnglish (US)
Title of host publication2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI
Pages708-711
Number of pages4
DOIs
StatePublished - 2008
Event2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI - Paris, France
Duration: May 14 2008May 17 2008

Other

Other2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI
CountryFrance
CityParis
Period5/14/085/17/08

Keywords

  • Diffusion tensor images
  • Medial modeling
  • Surface-based modeling
  • White matter modeling

ASJC Scopus subject areas

  • Biomedical Engineering

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    Zhang, H., Yushkevich, P. A., Simon, T. J., & Gee, J. C. (2008). Surface-based modeling of white matter fasciculi with orientation encoding. In 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI (pp. 708-711). [4541094] https://doi.org/10.1109/ISBI.2008.4541094