Surf early to higher tides: surfactant therapy to optimize tidal volume, lung recruitment, and iNO response

Girija G. Konduri, Satyan Lakshminrusimha

Research output: Contribution to journalEditorialpeer-review

Abstract

Inhaled nitric oxide is approved by FDA for the management of hypoxemic respiratory failure in term and near-term infants. However, approximately a third of patients treated with inhaled nitric oxide fail to have a sustained improvement in oxygenation. Recruitment of the lung with surfactant enables optimal delivery of nitric oxide to the alveolar space leading to effective pulmonary vasodilation.

Original languageEnglish (US)
JournalJournal of Perinatology
DOIs
StateAccepted/In press - 2020

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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