Suppression of in vitro lymphocyte transformation by serum from dogs with generalized demodicosis.

D. C. Hirsh, B. B. Baker, N. Wiger, S. G. Yaskulski, Bennie Osburn

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37 Scopus citations

Abstract

Serum from dogs with generalized demodicosis suppressed the in vitro reactivity of peripheral lymphocytes to phytohemagglutinin. Suppression occurred with peripheral lymphocytes from normal dogs or from dogs with generalized demodicosis. Serums from dogs in remission were no longer suppressive. The data indicate that peripheral lymphoid cells obtained from dogs with generalized demodicosis do not respond differently in vitro to phytohemagglutinin than do lymphoid cells from normal dogs when either is cultured in the presence of serum from normal dogs.

Original languageEnglish (US)
Pages (from-to)1591-1595
Number of pages5
JournalAmerican Journal of Veterinary Research
Volume36
Issue number11
StatePublished - Nov 1 1975
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)

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    Hirsh, D. C., Baker, B. B., Wiger, N., Yaskulski, S. G., & Osburn, B. (1975). Suppression of in vitro lymphocyte transformation by serum from dogs with generalized demodicosis. American Journal of Veterinary Research, 36(11), 1591-1595.