Superficial temporal artery calcification in patients with end-stage renal disease

Association with vascular risk factors and ischemic cerebrovascular disease

Zeeshan Anwar, Elcin Zan, Marco Carone, Arzu Ozturk, Stephen M. Sozio, David M. Yousem

Research output: Contribution to journalArticle

Abstract

Background and Purpose: Extracranial superficial temporal artery (STA) calcification is an unusual finding seen in patients with chronic kidney disease and has unknown ramifications with respect to intracranial ischemic disease. We sought to determine the association between the risk factors for vascular calcification and this rare phenomenon, in patients with chronic renal failure, and to assess the coexistence of cerebral ischemia. Materials and Methods: Medical records and laboratory data on risk factors for vascular calcification were retrospectively retrieved for 453 patients with a discharge diagnosis of end-stage renal disease (ESRD). CT head examinations were reviewed to identify and associate STA calcification with 1) risk factors for the vascular calcification, 2) intracranial artery calcification, and 3) cerebral ischemia (white matter and/or cortical ischemic changes). Results: STA calcification was present in 9.9% (45/453) of the studied cohort. The prevalence of cerebral ischemia was 24.4% (11/45) in patients with STA calcification and 9.3% (38/408) in patients without it. Diabetes mellitus (OR: 2.56, 95% CI: 1.059-6.208; P=0.037) was independently associated with the risk of STA calcification. The risk of cerebral ischemia, however, was not related to STA calcification (P=0.221). Conclusion: The presence of diabetes mellitus is important in describing the risk of STA calcification in patients with ESRD, whereas age, gender, hypertension, serum calcium, serum phosphate, or serum hemoglobin levels are not. The risk of cerebral ischemia is not related to STA calcification but has the strongest association with diabetes mellitus.

Original languageEnglish (US)
Pages (from-to)215-220
Number of pages6
JournalIndian Journal of Radiology and Imaging
Volume21
Issue number3
DOIs
StatePublished - Aug 2011
Externally publishedYes

Fingerprint

Cerebrovascular Disorders
Temporal Arteries
Chronic Kidney Failure
Brain Ischemia
Vascular Calcification
Diabetes Mellitus
Serum
vascular factor
Chronic Renal Insufficiency
Medical Records
Hemoglobins
Arteries
Head
Hypertension

Keywords

  • Cerebrovascular disease
  • end-stage renal disease
  • superficial temporal artery calcification

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Superficial temporal artery calcification in patients with end-stage renal disease : Association with vascular risk factors and ischemic cerebrovascular disease. / Anwar, Zeeshan; Zan, Elcin; Carone, Marco; Ozturk, Arzu; Sozio, Stephen M.; Yousem, David M.

In: Indian Journal of Radiology and Imaging, Vol. 21, No. 3, 08.2011, p. 215-220.

Research output: Contribution to journalArticle

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