Abstract
Purpose: To report the interval courses of previously reported cases of superficial hypertrophic dendriform epitheliopathy (SHDE) and to describe 3 new cases of this uncommon entity following penetrating keratoplasty. Method: Retrospective chart review. Results: We report follow-up on 3 previously described cases of SHDE, including discussion of cases and their clinical course. All 3 patients had persistent surface abnormalities complicating graft success resulting in poor visual outcomes. Three new cases of SHDE are discussed with a summary of the ocular findings and treatment. All patients underwent multiple penetrating keratoplasties for recurrent graft failures resulting from chronic postkeratoplasty surface keratopathy. Conclusions: SHDE is a rare complication of penetrating keratoplasty that can lead to delayed healing, chronic derangement of the corneal surface, corneal scarring, and an increased risk of graft rejection. Understanding and recognizing this entity is crucial for maximizing graft outcomes. Further investigation of the pathogenesis is necessary for complete understanding and management of the disorder.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 273-276 |
| Number of pages | 4 |
| Journal | Cornea |
| Volume | 25 |
| Issue number | 3 |
| DOIs | |
| State | Published - Apr 2006 |
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Keywords
- Corneal surface
- Dendriform epitheliopathy
- Keratoplasty
- Superficial hypertrophic dendriform epitheliopathy
ASJC Scopus subject areas
- Ophthalmology
Cite this
Superficial hypertrophic dendriform epitheliopathy : A follow-up series. / Lee, W. Barry; Mannis, Mark J; Mehra, Neal; Garcia-Ferrer, Francisco.
In: Cornea, Vol. 25, No. 3, 04.2006, p. 273-276.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Superficial hypertrophic dendriform epitheliopathy
T2 - A follow-up series
AU - Lee, W. Barry
AU - Mannis, Mark J
AU - Mehra, Neal
AU - Garcia-Ferrer, Francisco
PY - 2006/4
Y1 - 2006/4
N2 - Purpose: To report the interval courses of previously reported cases of superficial hypertrophic dendriform epitheliopathy (SHDE) and to describe 3 new cases of this uncommon entity following penetrating keratoplasty. Method: Retrospective chart review. Results: We report follow-up on 3 previously described cases of SHDE, including discussion of cases and their clinical course. All 3 patients had persistent surface abnormalities complicating graft success resulting in poor visual outcomes. Three new cases of SHDE are discussed with a summary of the ocular findings and treatment. All patients underwent multiple penetrating keratoplasties for recurrent graft failures resulting from chronic postkeratoplasty surface keratopathy. Conclusions: SHDE is a rare complication of penetrating keratoplasty that can lead to delayed healing, chronic derangement of the corneal surface, corneal scarring, and an increased risk of graft rejection. Understanding and recognizing this entity is crucial for maximizing graft outcomes. Further investigation of the pathogenesis is necessary for complete understanding and management of the disorder.
AB - Purpose: To report the interval courses of previously reported cases of superficial hypertrophic dendriform epitheliopathy (SHDE) and to describe 3 new cases of this uncommon entity following penetrating keratoplasty. Method: Retrospective chart review. Results: We report follow-up on 3 previously described cases of SHDE, including discussion of cases and their clinical course. All 3 patients had persistent surface abnormalities complicating graft success resulting in poor visual outcomes. Three new cases of SHDE are discussed with a summary of the ocular findings and treatment. All patients underwent multiple penetrating keratoplasties for recurrent graft failures resulting from chronic postkeratoplasty surface keratopathy. Conclusions: SHDE is a rare complication of penetrating keratoplasty that can lead to delayed healing, chronic derangement of the corneal surface, corneal scarring, and an increased risk of graft rejection. Understanding and recognizing this entity is crucial for maximizing graft outcomes. Further investigation of the pathogenesis is necessary for complete understanding and management of the disorder.
KW - Corneal surface
KW - Dendriform epitheliopathy
KW - Keratoplasty
KW - Superficial hypertrophic dendriform epitheliopathy
UR - http://www.scopus.com/inward/record.url?scp=33645971956&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33645971956&partnerID=8YFLogxK
U2 - 10.1097/01.ico.0000177836.31249.50
DO - 10.1097/01.ico.0000177836.31249.50
M3 - Article
C2 - 16633025
AN - SCOPUS:33645971956
VL - 25
SP - 273
EP - 276
JO - Cornea
JF - Cornea
SN - 0277-3740
IS - 3
ER -