Super-resolved spatial light interference microscopy

Kaiqin Chu; Zachary J. Smith; Sebastian Wachsmann-Hogiu; Stephen Lane

doi:10.1364/JOSAA.29.000344

Super-resolved spatial light interference microscopy

Kaiqin Chu, Zachary J. Smith, Sebastian Wachsmann-Hogiu, Stephen Lane

Pathology and Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

We report a scheme to achieve resolution beyond the diffraction limit in spatial light interference microscopy (SLIM). By adding a grating to the optical path, the structured illumination technique can be used to improve the resolution by a factor of 2. We show that a direct application of the structured illumination technique, however, has proved to be unsuccessful. Through two crucial modifications, namel y, one to the pupil plane of the objective and the other to the demodulation procedure, faithful phase information of the object is recovered and the resolution is improved by a factor of 2.

Original language	English (US)
Pages (from-to)	344-351
Number of pages	8
Journal	Journal of the Optical Society of America A: Optics and Image Science, and Vision
Volume	29
Issue number	3
DOIs	https://doi.org/10.1364/JOSAA.29.000344
State	Published - 2012

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Computer Vision and Pattern Recognition
Medicine(all)

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Super-resolved spatial light interference microscopy

Abstract

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