Suction sclerotherapy for the treatment of esophageal varices

A report of a preliminary feasibility study

Todd H. Baron, John G. Lee, Daniel I. Schenkman, Theodore N. Pappas, Joseph Leung

Research output: Contribution to journalArticle

Abstract

We report a new treatment modality for esophageal varices, suction sclerotherapy, which was designed to lift away mucosa and submucosa during treatment to prevent deep injection and resultant esophageal ulcerations. In order to compare the posttreatment complications of suction sclerotherapy against freehand sclerotherapy, we randomized 4 mongrel dogs to receive ten injections of 0.5-ml aliquots of absolute alcohol into the esophagus by either the suction or freehand sclerotherapy technique. The animals were humanely sacrificed after 48 h and examined. A total of five large, deep, confluent ulcers, free perforation, and lung abscess were seen in the animals randomized to freehand sclerotherapy. In contrast, a total of 14 shallow, discrete, erythematous lesions were found in the suction sclerotherapy group; none of these lesions extended deeper than the submucosa. We conclude that suction sclerotherapy produced local complications limited to the submucosa which were less severe as compared with freehand sclerotherapy.

Original languageEnglish (US)
Pages (from-to)356-361
Number of pages6
JournalDigestive Diseases
Volume14
Issue number6
StatePublished - Nov 1996
Externally publishedYes

Fingerprint

Sclerotherapy
Esophageal and Gastric Varices
Suction
Feasibility Studies
Therapeutics
Lung Abscess
Injections
Esophagus
Ulcer
Mucous Membrane
Ethanol
Dogs

Keywords

  • Band ligation
  • Endoscopy
  • Esophageal varices, therapy
  • Suction sclerotherapy, esophageal varices

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Suction sclerotherapy for the treatment of esophageal varices : A report of a preliminary feasibility study. / Baron, Todd H.; Lee, John G.; Schenkman, Daniel I.; Pappas, Theodore N.; Leung, Joseph.

In: Digestive Diseases, Vol. 14, No. 6, 11.1996, p. 356-361.

Research output: Contribution to journalArticle

Baron, Todd H. ; Lee, John G. ; Schenkman, Daniel I. ; Pappas, Theodore N. ; Leung, Joseph. / Suction sclerotherapy for the treatment of esophageal varices : A report of a preliminary feasibility study. In: Digestive Diseases. 1996 ; Vol. 14, No. 6. pp. 356-361.
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