Abstract
Background: The incidence of hemolytic disease of the fetus and newborn (HDFN) has decreased since the introduction of Rh immunoglobulin prophylaxis in Rh(D)-negative pregnant women. Thus, the relative incidence of rare alloantibody-related HDFN has increased. The lack of available maternally matched red blood cells for transfusion in these cases may create management difficulties. Case: We report a case of anti-Kpb HDFN. Severe fetal anemia required intrauterine transfusion. Difficulty in obtaining Kpb-negative blood necessitated using the mother's donated RBCs. Conclusion: Severe HDFN with rare antibodies can be managed successfully using maternal blood.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 281-283 |
| Number of pages | 3 |
| Journal | Transfusion and Apheresis Science |
| Volume | 43 |
| Issue number | 3 |
| DOIs | |
| State | Published - Dec 2010 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Hematology
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Successful use of maternal blood in the management of severe hemolytic disease of the fetus and newborn due to anti-Kpb . / Bleile, Michelle J.; Rijhsinghani, Asha; Dwyre, Denis M; Raife, Thomas J.
In: Transfusion and Apheresis Science, Vol. 43, No. 3, 12.2010, p. 281-283.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Successful use of maternal blood in the management of severe hemolytic disease of the fetus and newborn due to anti-Kpb
AU - Bleile, Michelle J.
AU - Rijhsinghani, Asha
AU - Dwyre, Denis M
AU - Raife, Thomas J.
PY - 2010/12
Y1 - 2010/12
N2 - Background: The incidence of hemolytic disease of the fetus and newborn (HDFN) has decreased since the introduction of Rh immunoglobulin prophylaxis in Rh(D)-negative pregnant women. Thus, the relative incidence of rare alloantibody-related HDFN has increased. The lack of available maternally matched red blood cells for transfusion in these cases may create management difficulties. Case: We report a case of anti-Kpb HDFN. Severe fetal anemia required intrauterine transfusion. Difficulty in obtaining Kpb-negative blood necessitated using the mother's donated RBCs. Conclusion: Severe HDFN with rare antibodies can be managed successfully using maternal blood.
AB - Background: The incidence of hemolytic disease of the fetus and newborn (HDFN) has decreased since the introduction of Rh immunoglobulin prophylaxis in Rh(D)-negative pregnant women. Thus, the relative incidence of rare alloantibody-related HDFN has increased. The lack of available maternally matched red blood cells for transfusion in these cases may create management difficulties. Case: We report a case of anti-Kpb HDFN. Severe fetal anemia required intrauterine transfusion. Difficulty in obtaining Kpb-negative blood necessitated using the mother's donated RBCs. Conclusion: Severe HDFN with rare antibodies can be managed successfully using maternal blood.
UR - http://www.scopus.com/inward/record.url?scp=78649485318&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78649485318&partnerID=8YFLogxK
U2 - 10.1016/j.transci.2010.09.010
DO - 10.1016/j.transci.2010.09.010
M3 - Article
C2 - 20951648
AN - SCOPUS:78649485318
VL - 43
SP - 281
EP - 283
JO - Transfusion and Apheresis Science
JF - Transfusion and Apheresis Science
SN - 1473-0502
IS - 3
ER -