Successful use of maternal blood in the management of severe hemolytic disease of the fetus and newborn due to anti-Kpb

Michelle J. Bleile, Asha Rijhsinghani, Denis M Dwyre, Thomas J. Raife

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Background: The incidence of hemolytic disease of the fetus and newborn (HDFN) has decreased since the introduction of Rh immunoglobulin prophylaxis in Rh(D)-negative pregnant women. Thus, the relative incidence of rare alloantibody-related HDFN has increased. The lack of available maternally matched red blood cells for transfusion in these cases may create management difficulties. Case: We report a case of anti-Kpb HDFN. Severe fetal anemia required intrauterine transfusion. Difficulty in obtaining Kpb-negative blood necessitated using the mother's donated RBCs. Conclusion: Severe HDFN with rare antibodies can be managed successfully using maternal blood.

Original languageEnglish (US)
Pages (from-to)281-283
Number of pages3
JournalTransfusion and Apheresis Science
Volume43
Issue number3
DOIs
StatePublished - Dec 2010
Externally publishedYes

ASJC Scopus subject areas

  • Hematology

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