Successful intraoperative reversal of heparin with factor VII in a patient with protamine reaction

Kuan Chin Jean Chen, Darrin Payne, Alejandro Lazo-Langner, Ian Ross, Bob Kiaii

Research output: Contribution to journalArticlepeer-review

Abstract

Factor VII has been utilized to treat post-operative bleeding after cardiac surgery refractory to other intervention. We report the case of a patient who developed intractable bleeding after a severe protamine reaction following emergency repair of type A aortic dissection and was successfully treated with factor VII.

Original languageEnglish (US)
Pages (from-to)48-50
Number of pages3
JournalInnovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
Volume6
Issue number1
DOIs
StatePublished - Jan 2011
Externally publishedYes

Keywords

  • Aortic dissection
  • Heparin
  • Protamine reaction
  • Recombinant factor VIIa

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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