Subcutaneous panniculitis-like T-cell lymphoma: Pediatric case series demonstrating heterogeneous presentation and option for watchful waiting

Emily E. Johnston, Robert E. Leblanc, Jinah Kim, Jong Hee Chung, Jay Balagtas, Youn H. Kim, Michael P. Link

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) and primary cutaneous gamma delta T-cell lymphoma (PCGD-TCL) were initially both classified as subcutaneous panniculitis-like T-cell lymphoma. In 2008, SPTCL with alpha-beta T-cell receptor subtype was separated from primary cutaneous gamma delta T-cell lymphomas (PCGD-TCL). We report four pediatric cases that demonstrate the heterogeneity of each disease and show that PCGD-TCL in children can have an indolent course, whereas SPTCL can behave aggressively. Three patients had spontaneous, durable remissions without treatment, whereas the one patient with disease progression was treated successfully. Watchful waiting may thus be appropriate for initial management of children.

Original languageEnglish (US)
Pages (from-to)2025-2028
Number of pages4
JournalPediatric Blood and Cancer
Volume62
Issue number11
DOIs
StatePublished - Nov 1 2015

Keywords

  • Lymphoma
  • Medical oncology
  • Non-Hodgkin lymphoma
  • Oncology
  • Pediatric hematology/oncology
  • Subcutaneous panniculitis-like T-Cell lymphoma

ASJC Scopus subject areas

  • Oncology
  • Pediatrics, Perinatology, and Child Health
  • Hematology

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