Subclinical and clinical bluetongue disease in cattle: clinical, pathological and pathogenic considerations.

G. A. Anderson, J. L. Stott, L. J. Gershwin, B. I. Osburn

Research output: Contribution to journalArticle

20 Scopus citations


Calves immunized (sensitized) with alcide-inactivated bluetongue virus (BTV) developed immunoglobulin (Ig) E-specific antibody to BTV. Development of clinically apparent disease occurred after challenge with virulent BTV, and lesions correlated with peak levels of virus-specific IgE, an eosinophilic dermatitis, and high concentrations of histamine in the skin. IgE may be important in the pathogenesis of clinical bluetongue (BT) disease in cattle.

Original languageEnglish (US)
Pages (from-to)103-107
Number of pages5
JournalProgress in Clinical and Biological Research
StatePublished - 1985


ASJC Scopus subject areas

  • Medicine(all)

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