Subclinical and clinical bluetongue disease in cattle: clinical, pathological and pathogenic considerations.

G. A. Anderson, J. L. Stott, L. J. Gershwin, B. I. Osburn

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Calves immunized (sensitized) with alcide-inactivated bluetongue virus (BTV) developed immunoglobulin (Ig) E-specific antibody to BTV. Development of clinically apparent disease occurred after challenge with virulent BTV, and lesions correlated with peak levels of virus-specific IgE, an eosinophilic dermatitis, and high concentrations of histamine in the skin. IgE may be important in the pathogenesis of clinical bluetongue (BT) disease in cattle.

Original languageEnglish (US)
Pages (from-to)103-107
Number of pages5
JournalProgress in Clinical and Biological Research
Volume178
StatePublished - 1985

Fingerprint

Bluetongue
Bluetongue virus
Cattle Diseases
Immunoglobulin E
Dermatitis
Histamine
Viruses
Skin
Antibodies

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{37b1be223bb341b293e5b52884819802,
title = "Subclinical and clinical bluetongue disease in cattle: clinical, pathological and pathogenic considerations.",
abstract = "Calves immunized (sensitized) with alcide-inactivated bluetongue virus (BTV) developed immunoglobulin (Ig) E-specific antibody to BTV. Development of clinically apparent disease occurred after challenge with virulent BTV, and lesions correlated with peak levels of virus-specific IgE, an eosinophilic dermatitis, and high concentrations of histamine in the skin. IgE may be important in the pathogenesis of clinical bluetongue (BT) disease in cattle.",
author = "Anderson, {G. A.} and Stott, {J. L.} and Gershwin, {L. J.} and Osburn, {B. I.}",
year = "1985",
language = "English (US)",
volume = "178",
pages = "103--107",
journal = "Progress in Clinical and Biological Research",
issn = "0361-7742",
publisher = "John Wiley and Sons Inc.",

}

TY - JOUR

T1 - Subclinical and clinical bluetongue disease in cattle

T2 - clinical, pathological and pathogenic considerations.

AU - Anderson, G. A.

AU - Stott, J. L.

AU - Gershwin, L. J.

AU - Osburn, B. I.

PY - 1985

Y1 - 1985

N2 - Calves immunized (sensitized) with alcide-inactivated bluetongue virus (BTV) developed immunoglobulin (Ig) E-specific antibody to BTV. Development of clinically apparent disease occurred after challenge with virulent BTV, and lesions correlated with peak levels of virus-specific IgE, an eosinophilic dermatitis, and high concentrations of histamine in the skin. IgE may be important in the pathogenesis of clinical bluetongue (BT) disease in cattle.

AB - Calves immunized (sensitized) with alcide-inactivated bluetongue virus (BTV) developed immunoglobulin (Ig) E-specific antibody to BTV. Development of clinically apparent disease occurred after challenge with virulent BTV, and lesions correlated with peak levels of virus-specific IgE, an eosinophilic dermatitis, and high concentrations of histamine in the skin. IgE may be important in the pathogenesis of clinical bluetongue (BT) disease in cattle.

UR - http://www.scopus.com/inward/record.url?scp=0021902395&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021902395&partnerID=8YFLogxK

M3 - Article

C2 - 2989843

AN - SCOPUS:0021902395

VL - 178

SP - 103

EP - 107

JO - Progress in Clinical and Biological Research

JF - Progress in Clinical and Biological Research

SN - 0361-7742

ER -