Abstract
Calves immunized (sensitized) with alcide-inactivated bluetongue virus (BTV) developed immunoglobulin (Ig) E-specific antibody to BTV. Development of clinically apparent disease occurred after challenge with virulent BTV, and lesions correlated with peak levels of virus-specific IgE, an eosinophilic dermatitis, and high concentrations of histamine in the skin. IgE may be important in the pathogenesis of clinical bluetongue (BT) disease in cattle.
Original language | English (US) |
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Pages (from-to) | 103-107 |
Number of pages | 5 |
Journal | Progress in Clinical and Biological Research |
Volume | 178 |
State | Published - 1985 |
ASJC Scopus subject areas
- Medicine(all)