Studies on the effects of substituents on rate enhancements in intramolecular diels-alder reactions: Reasons for the gem-dimethyl effect

Michael E. Jung, Jacquelyn Gervay-Hague

Research output: Contribution to journalArticle

79 Scopus citations

Abstract

Comparison of the rates of cyclization of a series of 2-furfuryl methyl fumarates leads to the conclusion that the gem-dimethyl effect is due primarily to higher population of reactive rotamers.

Original languageEnglish (US)
Pages (from-to)2429-2432
Number of pages4
JournalTetrahedron Letters
Volume29
Issue number20
DOIs
StatePublished - 1988

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Fingerprint Dive into the research topics of 'Studies on the effects of substituents on rate enhancements in intramolecular diels-alder reactions: Reasons for the gem-dimethyl effect'. Together they form a unique fingerprint.

  • Cite this