Structural basis for on- and off-center responses in retinal bipolar cells

William K. Stell, Andrew Ishida, David O. Lightfoot

Research output: Contribution to journalArticle

156 Citations (Scopus)

Abstract

Electron microscopy of Golgi preparations of goldfish retina shows that dendrites of type a (hyperpolarizing, off-center) bipolar cells make wide cleft junctions unassociated with synoptic ribbons, while those of type b (depolarizing, oncenter) bipolar cells make narrow cleft junctions and synoptic ribbon contacts, with rods and cones. This suggests that wide cleft junctions are the site of sign-conserving, and narrow cleft junctions or ribbon contacts (or both) are the site of signinverting synoptic transmission from photoreceptors to bipolars.

Original languageEnglish (US)
Pages (from-to)1269-1271
Number of pages3
JournalScience
Volume198
Issue number4323
StatePublished - 1977
Externally publishedYes

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Retinal Bipolar Cells
Vertebrate Photoreceptor Cells
Goldfish
Dendrites
Retina
Electron Microscopy

ASJC Scopus subject areas

  • General

Cite this

Stell, W. K., Ishida, A., & Lightfoot, D. O. (1977). Structural basis for on- and off-center responses in retinal bipolar cells. Science, 198(4323), 1269-1271.

Structural basis for on- and off-center responses in retinal bipolar cells. / Stell, William K.; Ishida, Andrew; Lightfoot, David O.

In: Science, Vol. 198, No. 4323, 1977, p. 1269-1271.

Research output: Contribution to journalArticle

Stell, WK, Ishida, A & Lightfoot, DO 1977, 'Structural basis for on- and off-center responses in retinal bipolar cells', Science, vol. 198, no. 4323, pp. 1269-1271.
Stell WK, Ishida A, Lightfoot DO. Structural basis for on- and off-center responses in retinal bipolar cells. Science. 1977;198(4323):1269-1271.
Stell, William K. ; Ishida, Andrew ; Lightfoot, David O. / Structural basis for on- and off-center responses in retinal bipolar cells. In: Science. 1977 ; Vol. 198, No. 4323. pp. 1269-1271.
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