Structural and functional studies on the interstitial collagen genes.

B. de Crombrugghe, G. Liau, C. Setoyama, A. Schmidt, C. McKeon, Maria Mudryj

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

An understanding of the molecular mechanisms which control expression of the type I and III collagen genes may provide a rational basis for the design of more effective therapeutic approaches to fibrotic diseases. The structure of the interstitial collagen genes is reviewed and potential sites which could control their expression are examined. One approach to the study of the regulation of these genes consists in DNA-mediated gene transfection experiments and is discussed in this paper.

Original languageEnglish (US)
Pages (from-to)20-33
Number of pages14
JournalCiba Foundation symposium
Volume114
StatePublished - 1985
Externally publishedYes

Fingerprint

Collagen
Genes
Collagen Type III
Collagen Type I
Transfection
DNA
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

de Crombrugghe, B., Liau, G., Setoyama, C., Schmidt, A., McKeon, C., & Mudryj, M. (1985). Structural and functional studies on the interstitial collagen genes. Ciba Foundation symposium, 114, 20-33.

Structural and functional studies on the interstitial collagen genes. / de Crombrugghe, B.; Liau, G.; Setoyama, C.; Schmidt, A.; McKeon, C.; Mudryj, Maria.

In: Ciba Foundation symposium, Vol. 114, 1985, p. 20-33.

Research output: Contribution to journalArticle

de Crombrugghe, B, Liau, G, Setoyama, C, Schmidt, A, McKeon, C & Mudryj, M 1985, 'Structural and functional studies on the interstitial collagen genes.', Ciba Foundation symposium, vol. 114, pp. 20-33.
de Crombrugghe B, Liau G, Setoyama C, Schmidt A, McKeon C, Mudryj M. Structural and functional studies on the interstitial collagen genes. Ciba Foundation symposium. 1985;114:20-33.
de Crombrugghe, B. ; Liau, G. ; Setoyama, C. ; Schmidt, A. ; McKeon, C. ; Mudryj, Maria. / Structural and functional studies on the interstitial collagen genes. In: Ciba Foundation symposium. 1985 ; Vol. 114. pp. 20-33.
@article{dfb210028b98470386d8682926b7babf,
title = "Structural and functional studies on the interstitial collagen genes.",
abstract = "An understanding of the molecular mechanisms which control expression of the type I and III collagen genes may provide a rational basis for the design of more effective therapeutic approaches to fibrotic diseases. The structure of the interstitial collagen genes is reviewed and potential sites which could control their expression are examined. One approach to the study of the regulation of these genes consists in DNA-mediated gene transfection experiments and is discussed in this paper.",
author = "{de Crombrugghe}, B. and G. Liau and C. Setoyama and A. Schmidt and C. McKeon and Maria Mudryj",
year = "1985",
language = "English (US)",
volume = "114",
pages = "20--33",
journal = "CIBA Foundation Symposia",
issn = "0300-5208",
publisher = "Wiley Subscription Services",

}

TY - JOUR

T1 - Structural and functional studies on the interstitial collagen genes.

AU - de Crombrugghe, B.

AU - Liau, G.

AU - Setoyama, C.

AU - Schmidt, A.

AU - McKeon, C.

AU - Mudryj, Maria

PY - 1985

Y1 - 1985

N2 - An understanding of the molecular mechanisms which control expression of the type I and III collagen genes may provide a rational basis for the design of more effective therapeutic approaches to fibrotic diseases. The structure of the interstitial collagen genes is reviewed and potential sites which could control their expression are examined. One approach to the study of the regulation of these genes consists in DNA-mediated gene transfection experiments and is discussed in this paper.

AB - An understanding of the molecular mechanisms which control expression of the type I and III collagen genes may provide a rational basis for the design of more effective therapeutic approaches to fibrotic diseases. The structure of the interstitial collagen genes is reviewed and potential sites which could control their expression are examined. One approach to the study of the regulation of these genes consists in DNA-mediated gene transfection experiments and is discussed in this paper.

UR - http://www.scopus.com/inward/record.url?scp=0021778638&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021778638&partnerID=8YFLogxK

M3 - Article

C2 - 2998711

AN - SCOPUS:0021778638

VL - 114

SP - 20

EP - 33

JO - CIBA Foundation Symposia

JF - CIBA Foundation Symposia

SN - 0300-5208

ER -