Structural and functional studies on the interstitial collagen genes.

B. de Crombrugghe; G. Liau; C. Setoyama; A. Schmidt; C. McKeon; Maria Mudryj

Structural and functional studies on the interstitial collagen genes.

B. de Crombrugghe, G. Liau, C. Setoyama, A. Schmidt, C. McKeon, Maria Mudryj

Research output: Contribution to journal › Article › peer-review

Abstract

An understanding of the molecular mechanisms which control expression of the type I and III collagen genes may provide a rational basis for the design of more effective therapeutic approaches to fibrotic diseases. The structure of the interstitial collagen genes is reviewed and potential sites which could control their expression are examined. One approach to the study of the regulation of these genes consists in DNA-mediated gene transfection experiments and is discussed in this paper.

Original language	English (US)
Pages (from-to)	20-33
Number of pages	14
Journal	Ciba Foundation symposium
Volume	114
State	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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title = "Structural and functional studies on the interstitial collagen genes.",

abstract = "An understanding of the molecular mechanisms which control expression of the type I and III collagen genes may provide a rational basis for the design of more effective therapeutic approaches to fibrotic diseases. The structure of the interstitial collagen genes is reviewed and potential sites which could control their expression are examined. One approach to the study of the regulation of these genes consists in DNA-mediated gene transfection experiments and is discussed in this paper.",

author = "{de Crombrugghe}, B. and G. Liau and C. Setoyama and A. Schmidt and C. McKeon and Maria Mudryj",

year = "1985",

language = "English (US)",

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journal = "CIBA Foundation Symposia",

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T1 - Structural and functional studies on the interstitial collagen genes.

AU - de Crombrugghe, B.

AU - Liau, G.

AU - Setoyama, C.

AU - Schmidt, A.

AU - McKeon, C.

AU - Mudryj, Maria

PY - 1985

Y1 - 1985

N2 - An understanding of the molecular mechanisms which control expression of the type I and III collagen genes may provide a rational basis for the design of more effective therapeutic approaches to fibrotic diseases. The structure of the interstitial collagen genes is reviewed and potential sites which could control their expression are examined. One approach to the study of the regulation of these genes consists in DNA-mediated gene transfection experiments and is discussed in this paper.

AB - An understanding of the molecular mechanisms which control expression of the type I and III collagen genes may provide a rational basis for the design of more effective therapeutic approaches to fibrotic diseases. The structure of the interstitial collagen genes is reviewed and potential sites which could control their expression are examined. One approach to the study of the regulation of these genes consists in DNA-mediated gene transfection experiments and is discussed in this paper.

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JO - CIBA Foundation Symposia

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