Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins

Yun Chiao Yao, Amir Taqieddin, Mohammad A. Alibakhshi, Meni Wanunu, Narayana R. Aluru, Aleksandr Noy

Research output: Contribution to journalArticle

Abstract

Extreme confinement in nanometer-sized channels can alter fluid and ion transport in significant ways, leading to significant water flow enhancement and unusual ion correlation effects. These effects are especially pronounced in carbon nanotube porins (CNTPs) that combine strong confinement in the inner lumen of carbon nanotubes with the high slip flow enhancement due to smooth hydrophobic pore walls. We have studied ion transport and ion selectivity in 1.5 nm diameter CNTPs embedded in lipid membranes using a single nanopore measurement setup. Our data show that CNTPs are weakly cation selective at pH 7.5 and become nonselective at pH 3.0. Ion conductance of CNTPs exhibits an unusual 2/3 power law scaling with the ion concentration at both neutral and acidic pH values. Coupled Navier-Stokes and Poisson-Nernst-Planck simulations and atomistic molecular dynamics simulations reveal that this scaling originates from strong coupling between water and ion transport in these channels. These effects could result in development of a next generation of biomimetic membranes and carbon nanotube-based electroosmotic pumps.

Original languageEnglish (US)
JournalACS Nano
DOIs
StatePublished - Jan 1 2019

Fingerprint

Porins
Carbon Nanotubes
Carbon nanotubes
carbon nanotubes
Ions
ions
membranes
slip flow
lumens
augmentation
water flow
biomimetics
ion concentration
Nanopores
Water
Scaling laws
scaling laws
Biomimetics
Membrane Lipids
lipids

Keywords

  • carbon nanotube porins
  • electroosmosis
  • ion transport
  • nanofluidics
  • slip-flow coupling

ASJC Scopus subject areas

  • Materials Science(all)
  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins. / Yao, Yun Chiao; Taqieddin, Amir; Alibakhshi, Mohammad A.; Wanunu, Meni; Aluru, Narayana R.; Noy, Aleksandr.

In: ACS Nano, 01.01.2019.

Research output: Contribution to journalArticle

Yao, Yun Chiao ; Taqieddin, Amir ; Alibakhshi, Mohammad A. ; Wanunu, Meni ; Aluru, Narayana R. ; Noy, Aleksandr. / Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins. In: ACS Nano. 2019.
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