Streptococcus equi was isolated from a corneal ulcer in a horse. The ulcer developed as an extension of septic uveitis subsequent to submandibular lymphadenopathy. The condition was refractory to therapy and panophthalmitis ensued. The affected eye was enucleated and S. equi was isolated in pure culture from the anterior chamber. S. equi should be considered as an etiologic agent in cases of uveitis in the horse, especially if there is a recent history of strangles.
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