Stochastic model of porcine reproductive and respiratory syndrome virus control strategies on a swine farm in the United States

Jaewoon Jeong, Sharif S Aly, Jean Paul Cano, Dale Polson, Philip H Kass, Andres M. Perez

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective-To use mathematical modeling to assess the effectiveness of control strategies for porcine reproductive and respiratory syndrome (PRRS) virus on a swine farm. Sample-A hypothetical small, medium, or large farrow-to-weaning swine farm in the Midwestern United States. Procedures-Stochastic models were formulated to simulate an outbreak of PRRS on a farm. Control strategies assessed in those models included none (baseline) and various combinations of mass immunization, herd closure, and gilt acclimatization. Nine different models resulting from the combination of low, moderate, or high PRRS virus virulence and small, medium, or large herd size were simulated. A stabilized status, the outcome of interest, was defined as the absence of positive PCR assay results for PRRS virus in 3-week-old piglets. For each scenario, the percentage of simulations with a stabilized status was used as a proxy for the probability of disease control. Results-Increasing PRRS virus virulence and herd size were negatively associated with the probability of achieving a stabilized status. Repeated mass immunization with herd closure or gilt acclimitization was a better alternative than was single mass immunization for disease control within a farm. Conclusions and Clinical Relevance-Repeated mass immunization with a PRRS modified- live virus vaccine with herd closure or gilt acclimitization was the scenario most likely to achieve a stabilized status. Estimation of the cost of various PRRS control strategies is necessary.

Original languageEnglish (US)
Pages (from-to)260-267
Number of pages8
JournalAmerican Journal of Veterinary Research
Volume75
Issue number3
DOIs
StatePublished - Mar 2014

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Porcine respiratory and reproductive syndrome virus
Mass Vaccination
Porcine reproductive and respiratory syndrome virus
Porcine Reproductive and Respiratory Syndrome
porcine reproductive and respiratory syndrome
immunization
Swine
gilts
farms
swine
herd size
herds
Virulence
disease control
virulence
Midwestern United States
Acclimatization
Proxy
farrowing
Weaning

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Stochastic model of porcine reproductive and respiratory syndrome virus control strategies on a swine farm in the United States. / Jeong, Jaewoon; Aly, Sharif S; Cano, Jean Paul; Polson, Dale; Kass, Philip H; Perez, Andres M.

In: American Journal of Veterinary Research, Vol. 75, No. 3, 03.2014, p. 260-267.

Research output: Contribution to journalArticle

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