Stimulus contrast and retinogeniculate signal processing

Daniel L. Rathbun, Henry J. Alitto, David K. Warland, William Martin Usrey

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Neuronal signals conveying luminance contrast play a key role in nearly all aspects of perception, including depth perception, texture discrimination, and motion perception. Although much is known about the retinal mechanisms responsible for encoding contrast information, relatively little is known about the relationship between stimulus contrast and the processing of neuronal signals between visual structures. Here, we describe simultaneous recordings from monosynaptically connected retinal ganglion cells and lateral geniculate nucleus (LGN) neurons in the cat to determine how stimulus contrast affects the communication of visual signals between the two structures. Our results indicate that: (1) LGN neurons typically reach their half-maximal response at lower contrasts than their individual retinal inputs and (2) LGN neurons exhibit greater contrast-dependent phase advance (CDPA) than their retinal inputs. Further analyses suggests that increased sensitivity relies on spatial convergence of multiple retinal inputs, while increased CDPA is achieved, in part, on temporal summation of arriving signals.

Original languageEnglish (US)
Article number8
JournalFrontiers in Neural Circuits
Volume10
Issue numberFEB
DOIs
StatePublished - Feb 19 2016

Keywords

  • Coding
  • LGN
  • Retina
  • Thalamus
  • Vision

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Cellular and Molecular Neuroscience
  • Sensory Systems
  • Cognitive Neuroscience

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    Rathbun, D. L., Alitto, H. J., Warland, D. K., & Usrey, W. M. (2016). Stimulus contrast and retinogeniculate signal processing. Frontiers in Neural Circuits, 10(FEB), [8]. https://doi.org/10.3389/fncir.2016.00008