Abstract
Stereotactic radiation therapy (SRT) developed from its precursor, stereotactic neurosurgery. The term 'radiosurgery' was coined by neurosurgeon Lars Leksell in 1951 just as Sir Victor Horsley coined the term 'stereotaxis' in 1908. The originally published technique involved the precise direction of an external beam of radiation (x-ray, protons, gamma rays, or high energy photons) at a stereotactically defined target. Collaborations with nuclear physicists, beginning in Berkeley, California, in 1954, harnessed the penetration of extremely powerful protons and other light ions to ablate tumors located deep within the brain. Leksell and collaborators developed the Gamma Knife, a massive device containing 201 cobalt-60 sources precisely directed to an extremely small volume. It was used successfully in Stockholm for many years and later was commercialized and used all over the world. Existing linear accelerator radiation therapy treatment devices were later modified to mimic the Gamma Knife technique. Ultimately, dedicated SRT linear accelerators were marketed. These types of intracranial SRT proved so successful in treating brain disease that similar techniques (sometimes fractionated) were adapted for extracranial targets. Stereotactic body radiation therapy (SBRT) was first performed in Stockholm in the 1980s. Development of image-guided SBRT has become well accepted in modern radiation therapy departments.
| Original language | English (US) |
|---|---|
| Title of host publication | Comprehensive Biomedical Physics |
| Publisher | Elsevier |
| Pages | 505-527 |
| Number of pages | 23 |
| Volume | 9 |
| ISBN (Print) | 9780444536327, 9780444536334 |
| DOIs | |
| State | Published - Jul 25 2014 |
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Keywords
- Breath-hold techniques
- Cyberknife
- Flattening filter free
- Frameless
- Gamma Knife
- Immobilization
- Intracranial
- Maximum intensity projections (MIPs)
- Minimum intensity projections
- Radiosurgery
- Respiratory motion management
- Stereotactic body radiation therapy (SBRT)
- Stereotactic radiation therapy (SRT)
- Stereotactic radiosurgery (SRS)
- Stereotaxis
- Vero
ASJC Scopus subject areas
- Physics and Astronomy(all)
Cite this
Stereotactic Radiation Therapy. / Benedict, Stanley H; Perks, Julian R; Goetsch, S.; Wijesooriya, K.; Miften, M.; Vinogradskiy, Y.; Medin, P.; Descovich, M.; Lovelock, D. M.; Low, D. A.; Kry, S. F.
Comprehensive Biomedical Physics. Vol. 9 Elsevier, 2014. p. 505-527.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Stereotactic Radiation Therapy
AU - Benedict, Stanley H
AU - Perks, Julian R
AU - Goetsch, S.
AU - Wijesooriya, K.
AU - Miften, M.
AU - Vinogradskiy, Y.
AU - Medin, P.
AU - Descovich, M.
AU - Lovelock, D. M.
AU - Low, D. A.
AU - Kry, S. F.
PY - 2014/7/25
Y1 - 2014/7/25
N2 - Stereotactic radiation therapy (SRT) developed from its precursor, stereotactic neurosurgery. The term 'radiosurgery' was coined by neurosurgeon Lars Leksell in 1951 just as Sir Victor Horsley coined the term 'stereotaxis' in 1908. The originally published technique involved the precise direction of an external beam of radiation (x-ray, protons, gamma rays, or high energy photons) at a stereotactically defined target. Collaborations with nuclear physicists, beginning in Berkeley, California, in 1954, harnessed the penetration of extremely powerful protons and other light ions to ablate tumors located deep within the brain. Leksell and collaborators developed the Gamma Knife, a massive device containing 201 cobalt-60 sources precisely directed to an extremely small volume. It was used successfully in Stockholm for many years and later was commercialized and used all over the world. Existing linear accelerator radiation therapy treatment devices were later modified to mimic the Gamma Knife technique. Ultimately, dedicated SRT linear accelerators were marketed. These types of intracranial SRT proved so successful in treating brain disease that similar techniques (sometimes fractionated) were adapted for extracranial targets. Stereotactic body radiation therapy (SBRT) was first performed in Stockholm in the 1980s. Development of image-guided SBRT has become well accepted in modern radiation therapy departments.
AB - Stereotactic radiation therapy (SRT) developed from its precursor, stereotactic neurosurgery. The term 'radiosurgery' was coined by neurosurgeon Lars Leksell in 1951 just as Sir Victor Horsley coined the term 'stereotaxis' in 1908. The originally published technique involved the precise direction of an external beam of radiation (x-ray, protons, gamma rays, or high energy photons) at a stereotactically defined target. Collaborations with nuclear physicists, beginning in Berkeley, California, in 1954, harnessed the penetration of extremely powerful protons and other light ions to ablate tumors located deep within the brain. Leksell and collaborators developed the Gamma Knife, a massive device containing 201 cobalt-60 sources precisely directed to an extremely small volume. It was used successfully in Stockholm for many years and later was commercialized and used all over the world. Existing linear accelerator radiation therapy treatment devices were later modified to mimic the Gamma Knife technique. Ultimately, dedicated SRT linear accelerators were marketed. These types of intracranial SRT proved so successful in treating brain disease that similar techniques (sometimes fractionated) were adapted for extracranial targets. Stereotactic body radiation therapy (SBRT) was first performed in Stockholm in the 1980s. Development of image-guided SBRT has become well accepted in modern radiation therapy departments.
KW - Breath-hold techniques
KW - Cyberknife
KW - Flattening filter free
KW - Frameless
KW - Gamma Knife
KW - Immobilization
KW - Intracranial
KW - Maximum intensity projections (MIPs)
KW - Minimum intensity projections
KW - Radiosurgery
KW - Respiratory motion management
KW - Stereotactic body radiation therapy (SBRT)
KW - Stereotactic radiation therapy (SRT)
KW - Stereotactic radiosurgery (SRS)
KW - Stereotaxis
KW - Vero
UR - http://www.scopus.com/inward/record.url?scp=84943418784&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84943418784&partnerID=8YFLogxK
U2 - 10.1016/B978-0-444-53632-7.00925-4
DO - 10.1016/B978-0-444-53632-7.00925-4
M3 - Chapter
AN - SCOPUS:84943418784
SN - 9780444536327
SN - 9780444536334
VL - 9
SP - 505
EP - 527
BT - Comprehensive Biomedical Physics
PB - Elsevier
ER -