Stereotactic body radiotherapy (SBRT)

Yasushi Nagata, Kenji Takayama, Yukinori Matsuo, Yoshiki Norihisa, Takashi Mizowaki, Masato Sakamoto, Shinsuke Yano, Yuichiro Narita, Tokihiro Yamamoto, Masahiro Hiraoka

Research output: Contribution to journalArticle

Abstract

The techniques of three-dimensional conformal radiotherapy (3 D-CRT) and patient immobilization have recently been developed, enabling us to focus high doses on the target with relatively less irradiation of normal tissues. In radiotherapy for solitary lung tumors, the local control may be safely improved by delivering a higher dose at only the target volume using these techniques. Recently, several clinical studies on stereotactic body radiotherapy (SRT) using the 3 D-CRT technique for solitary lung tumors have been reported. The single dose used is 10-15 Gy, and the total sessions are three to five. The local control rate is more than 90% and complication rates are very low. Therefore, this treatment is a promising new non-invasive treatment for early stage lung cancer. A multi-institutional clinical study, JCOG 0403, in now underway.

Original languageEnglish (US)
Pages (from-to)455-461
Number of pages7
JournalGan to kagaku ryoho. Cancer & chemotherapy.
Volume33
Issue number4
StatePublished - Apr 2006
Externally publishedYes

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Radiosurgery
Conformal Radiotherapy
Lung
Immobilization
Lung Neoplasms
Neoplasms
Radiotherapy
Therapeutics
Clinical Studies

ASJC Scopus subject areas

  • Cancer Research
  • Pharmacology

Cite this

Nagata, Y., Takayama, K., Matsuo, Y., Norihisa, Y., Mizowaki, T., Sakamoto, M., ... Hiraoka, M. (2006). Stereotactic body radiotherapy (SBRT). Gan to kagaku ryoho. Cancer & chemotherapy., 33(4), 455-461.

Stereotactic body radiotherapy (SBRT). / Nagata, Yasushi; Takayama, Kenji; Matsuo, Yukinori; Norihisa, Yoshiki; Mizowaki, Takashi; Sakamoto, Masato; Yano, Shinsuke; Narita, Yuichiro; Yamamoto, Tokihiro; Hiraoka, Masahiro.

In: Gan to kagaku ryoho. Cancer & chemotherapy., Vol. 33, No. 4, 04.2006, p. 455-461.

Research output: Contribution to journalArticle

Nagata, Y, Takayama, K, Matsuo, Y, Norihisa, Y, Mizowaki, T, Sakamoto, M, Yano, S, Narita, Y, Yamamoto, T & Hiraoka, M 2006, 'Stereotactic body radiotherapy (SBRT)', Gan to kagaku ryoho. Cancer & chemotherapy., vol. 33, no. 4, pp. 455-461.
Nagata Y, Takayama K, Matsuo Y, Norihisa Y, Mizowaki T, Sakamoto M et al. Stereotactic body radiotherapy (SBRT). Gan to kagaku ryoho. Cancer & chemotherapy. 2006 Apr;33(4):455-461.
Nagata, Yasushi ; Takayama, Kenji ; Matsuo, Yukinori ; Norihisa, Yoshiki ; Mizowaki, Takashi ; Sakamoto, Masato ; Yano, Shinsuke ; Narita, Yuichiro ; Yamamoto, Tokihiro ; Hiraoka, Masahiro. / Stereotactic body radiotherapy (SBRT). In: Gan to kagaku ryoho. Cancer & chemotherapy. 2006 ; Vol. 33, No. 4. pp. 455-461.
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AU - Mizowaki, Takashi

AU - Sakamoto, Masato

AU - Yano, Shinsuke

AU - Narita, Yuichiro

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AU - Hiraoka, Masahiro

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