Stereotactic body radiation therapy: Rationale, techniques, applications, and optimization

Danny Y. Song, Brian D. Kavanagh, Stanley H Benedict, Tracey Schefter

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Stereotatic body radiation therapy (SBRT) is a rapidly evolving cancer treatment method in which concepts and techniques previously developed for brain tumor radiosurgery are adapted to eradicate tumors elsewhere in the body. The spatial accuracy, conformality, and steep radiation dose gradients of radiosurgery, which have been critical to its success in the treatment of intracranial tumors, are applied in SBRT to treat a variety of extracranial tumors. Early results demonstrate excellent response rates and low toxicity with a variety of hypofractionated dose regimens and localization/immobilization techniques. This article provides an overview of the rationale and results of SBRT for specific indications, descriptions of some methods of treatment delivery, and discussion of potential areas of future investigation.

Original languageEnglish (US)
Pages (from-to)1419-1430
Number of pages12
JournalOncology
Volume18
Issue number11
StatePublished - Oct 2004
Externally publishedYes

Fingerprint

Radiotherapy
Radiosurgery
Neoplasms
Brain Neoplasms
Immobilization
Therapeutics
Radiation

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Stereotactic body radiation therapy : Rationale, techniques, applications, and optimization. / Song, Danny Y.; Kavanagh, Brian D.; Benedict, Stanley H; Schefter, Tracey.

In: Oncology, Vol. 18, No. 11, 10.2004, p. 1419-1430.

Research output: Contribution to journalArticle

Song, DY, Kavanagh, BD, Benedict, SH & Schefter, T 2004, 'Stereotactic body radiation therapy: Rationale, techniques, applications, and optimization', Oncology, vol. 18, no. 11, pp. 1419-1430.
Song, Danny Y. ; Kavanagh, Brian D. ; Benedict, Stanley H ; Schefter, Tracey. / Stereotactic body radiation therapy : Rationale, techniques, applications, and optimization. In: Oncology. 2004 ; Vol. 18, No. 11. pp. 1419-1430.
@article{6d8d895a17f342edba6c7e4b362fe053,
title = "Stereotactic body radiation therapy: Rationale, techniques, applications, and optimization",
abstract = "Stereotatic body radiation therapy (SBRT) is a rapidly evolving cancer treatment method in which concepts and techniques previously developed for brain tumor radiosurgery are adapted to eradicate tumors elsewhere in the body. The spatial accuracy, conformality, and steep radiation dose gradients of radiosurgery, which have been critical to its success in the treatment of intracranial tumors, are applied in SBRT to treat a variety of extracranial tumors. Early results demonstrate excellent response rates and low toxicity with a variety of hypofractionated dose regimens and localization/immobilization techniques. This article provides an overview of the rationale and results of SBRT for specific indications, descriptions of some methods of treatment delivery, and discussion of potential areas of future investigation.",
author = "Song, {Danny Y.} and Kavanagh, {Brian D.} and Benedict, {Stanley H} and Tracey Schefter",
year = "2004",
month = "10",
language = "English (US)",
volume = "18",
pages = "1419--1430",
journal = "Oncology",
issn = "0890-9091",
publisher = "UBM Medica Healthcare Publications",
number = "11",

}

TY - JOUR

T1 - Stereotactic body radiation therapy

T2 - Rationale, techniques, applications, and optimization

AU - Song, Danny Y.

AU - Kavanagh, Brian D.

AU - Benedict, Stanley H

AU - Schefter, Tracey

PY - 2004/10

Y1 - 2004/10

N2 - Stereotatic body radiation therapy (SBRT) is a rapidly evolving cancer treatment method in which concepts and techniques previously developed for brain tumor radiosurgery are adapted to eradicate tumors elsewhere in the body. The spatial accuracy, conformality, and steep radiation dose gradients of radiosurgery, which have been critical to its success in the treatment of intracranial tumors, are applied in SBRT to treat a variety of extracranial tumors. Early results demonstrate excellent response rates and low toxicity with a variety of hypofractionated dose regimens and localization/immobilization techniques. This article provides an overview of the rationale and results of SBRT for specific indications, descriptions of some methods of treatment delivery, and discussion of potential areas of future investigation.

AB - Stereotatic body radiation therapy (SBRT) is a rapidly evolving cancer treatment method in which concepts and techniques previously developed for brain tumor radiosurgery are adapted to eradicate tumors elsewhere in the body. The spatial accuracy, conformality, and steep radiation dose gradients of radiosurgery, which have been critical to its success in the treatment of intracranial tumors, are applied in SBRT to treat a variety of extracranial tumors. Early results demonstrate excellent response rates and low toxicity with a variety of hypofractionated dose regimens and localization/immobilization techniques. This article provides an overview of the rationale and results of SBRT for specific indications, descriptions of some methods of treatment delivery, and discussion of potential areas of future investigation.

UR - http://www.scopus.com/inward/record.url?scp=16644368861&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=16644368861&partnerID=8YFLogxK

M3 - Article

C2 - 15609470

AN - SCOPUS:16644368861

VL - 18

SP - 1419

EP - 1430

JO - Oncology

JF - Oncology

SN - 0890-9091

IS - 11

ER -