Stannous chloride in alcohol

A one-pot conversion of 2-Nitro-N- arylbenzamides to 2,3-Dihydro-1H-quinazoline-4-ones

Choong Leol Yoo, James C. Fettinger, Mark J. Kurth

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

A novel one-step synthesis of 2,3-dihydro-1H-quinazolin-4-ones from 2-nitrobenzamides is reported. These reactions are mediated by stannous chloride in 0.02 M methanolic or ethanolic HCl solution and proceed in good yields.

Original languageEnglish (US)
Pages (from-to)6941-6943
Number of pages3
JournalJournal of Organic Chemistry
Volume70
Issue number17
DOIs
StatePublished - Aug 19 2005

Fingerprint

Quinazolines
Alcohols
4-hydroxyquinazoline
stannous chloride

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Stannous chloride in alcohol : A one-pot conversion of 2-Nitro-N- arylbenzamides to 2,3-Dihydro-1H-quinazoline-4-ones. / Yoo, Choong Leol; Fettinger, James C.; Kurth, Mark J.

In: Journal of Organic Chemistry, Vol. 70, No. 17, 19.08.2005, p. 6941-6943.

Research output: Contribution to journalArticle

Yoo, Choong Leol ; Fettinger, James C. ; Kurth, Mark J. / Stannous chloride in alcohol : A one-pot conversion of 2-Nitro-N- arylbenzamides to 2,3-Dihydro-1H-quinazoline-4-ones. In: Journal of Organic Chemistry. 2005 ; Vol. 70, No. 17. pp. 6941-6943.
@article{0c8fdf6660d2488a9adf922dab290c6e,
title = "Stannous chloride in alcohol: A one-pot conversion of 2-Nitro-N- arylbenzamides to 2,3-Dihydro-1H-quinazoline-4-ones",
abstract = "A novel one-step synthesis of 2,3-dihydro-1H-quinazolin-4-ones from 2-nitrobenzamides is reported. These reactions are mediated by stannous chloride in 0.02 M methanolic or ethanolic HCl solution and proceed in good yields.",
author = "Yoo, {Choong Leol} and Fettinger, {James C.} and Kurth, {Mark J.}",
year = "2005",
month = "8",
day = "19",
doi = "10.1021/jo050450f",
language = "English (US)",
volume = "70",
pages = "6941--6943",
journal = "Journal of Organic Chemistry",
issn = "0022-3263",
publisher = "American Chemical Society",
number = "17",

}

TY - JOUR

T1 - Stannous chloride in alcohol

T2 - A one-pot conversion of 2-Nitro-N- arylbenzamides to 2,3-Dihydro-1H-quinazoline-4-ones

AU - Yoo, Choong Leol

AU - Fettinger, James C.

AU - Kurth, Mark J.

PY - 2005/8/19

Y1 - 2005/8/19

N2 - A novel one-step synthesis of 2,3-dihydro-1H-quinazolin-4-ones from 2-nitrobenzamides is reported. These reactions are mediated by stannous chloride in 0.02 M methanolic or ethanolic HCl solution and proceed in good yields.

AB - A novel one-step synthesis of 2,3-dihydro-1H-quinazolin-4-ones from 2-nitrobenzamides is reported. These reactions are mediated by stannous chloride in 0.02 M methanolic or ethanolic HCl solution and proceed in good yields.

UR - http://www.scopus.com/inward/record.url?scp=23644454407&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=23644454407&partnerID=8YFLogxK

U2 - 10.1021/jo050450f

DO - 10.1021/jo050450f

M3 - Article

VL - 70

SP - 6941

EP - 6943

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

SN - 0022-3263

IS - 17

ER -