Stabilizing and Remodeling the Blocked DNA Replication Fork: Anchoring FANCM and the Fanconi Anemia Damage Response

Larry H. Thompson, Nigel J. Jones

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

In this issue of Molecular Cell, Yan et al. (2010) and Singh et al. (2010) identify an evolutionarily conserved FANCM-associated histone-fold MHF heterodimer (MHF1-MHF2) that promotes the remodeling of artificial replication forks and confers cellular resistance to DNA crosslinks and camptothecin.

Original languageEnglish (US)
Pages (from-to)749-751
Number of pages3
JournalMolecular Cell
Volume37
Issue number6
DOIs
StatePublished - Mar 26 2010
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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