Spray pyrolysis synthesis of particles possessing magnetic and fluorescent properties. Application of magnetic/fluorescent particles in immunoassays

D. Dosev, M. Nichkova, R. Dumas, K. Liu, I. M. Kennedy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Many types of fluorescent nanoparticles have been synthesized as alternatives to organic dyes in biochemistry. Magnetic beads also have a long history of biological applications. In this work we apply flame spray pyrolysis in order to engineer a novel type of particle that has both fluorescent and magnetic properties. The particles have magnetic cores of iron oxide and a fluorescent shell of europium - doped gadolinium oxide (Eu:Gd 2O 3). Measurements on a Vibrating Sample Magnetometer showed an overall paramagnetic response behavior of the composite particles. Fluorescence spectroscopy showed fluorescent spectra typical for the Eu ion in a Gd 2O 3 host with a narrow emission peak centered near 615 nm. Our synthesis method provides a low-cost, high-rate synthesis that allows a wide range of biological applications of magnetic/fluorescent core/shell particles. We show an immunoassay using the fluorescent properties of the particles.

Original languageEnglish (US)
Title of host publicationAIChE Annual Meeting, Conference Proceedings
Pages11352-11364
Number of pages13
StatePublished - 2005
Event05AIChE: 2005 AIChE Annual Meeting and Fall Showcase - Cincinnati, OH, United States
Duration: Oct 30 2005Nov 4 2005

Other

Other05AIChE: 2005 AIChE Annual Meeting and Fall Showcase
CountryUnited States
CityCincinnati, OH
Period10/30/0511/4/05

Fingerprint

Spray pyrolysis
Magnetic cores
Biochemistry
Europium
Gadolinium
Fluorescence spectroscopy
Magnetometers
Iron oxides
Magnetic properties
Dyes
Nanoparticles
Engineers
Oxides
Composite materials
Ions
Costs

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Dosev, D., Nichkova, M., Dumas, R., Liu, K., & Kennedy, I. M. (2005). Spray pyrolysis synthesis of particles possessing magnetic and fluorescent properties. Application of magnetic/fluorescent particles in immunoassays. In AIChE Annual Meeting, Conference Proceedings (pp. 11352-11364)

Spray pyrolysis synthesis of particles possessing magnetic and fluorescent properties. Application of magnetic/fluorescent particles in immunoassays. / Dosev, D.; Nichkova, M.; Dumas, R.; Liu, K.; Kennedy, I. M.

AIChE Annual Meeting, Conference Proceedings. 2005. p. 11352-11364.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Dosev, D, Nichkova, M, Dumas, R, Liu, K & Kennedy, IM 2005, Spray pyrolysis synthesis of particles possessing magnetic and fluorescent properties. Application of magnetic/fluorescent particles in immunoassays. in AIChE Annual Meeting, Conference Proceedings. pp. 11352-11364, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Cincinnati, OH, United States, 10/30/05.
Dosev D, Nichkova M, Dumas R, Liu K, Kennedy IM. Spray pyrolysis synthesis of particles possessing magnetic and fluorescent properties. Application of magnetic/fluorescent particles in immunoassays. In AIChE Annual Meeting, Conference Proceedings. 2005. p. 11352-11364
Dosev, D. ; Nichkova, M. ; Dumas, R. ; Liu, K. ; Kennedy, I. M. / Spray pyrolysis synthesis of particles possessing magnetic and fluorescent properties. Application of magnetic/fluorescent particles in immunoassays. AIChE Annual Meeting, Conference Proceedings. 2005. pp. 11352-11364
@inproceedings{ecf4ae029abd45679c81ee108c4ccbf7,
title = "Spray pyrolysis synthesis of particles possessing magnetic and fluorescent properties. Application of magnetic/fluorescent particles in immunoassays",
abstract = "Many types of fluorescent nanoparticles have been synthesized as alternatives to organic dyes in biochemistry. Magnetic beads also have a long history of biological applications. In this work we apply flame spray pyrolysis in order to engineer a novel type of particle that has both fluorescent and magnetic properties. The particles have magnetic cores of iron oxide and a fluorescent shell of europium - doped gadolinium oxide (Eu:Gd 2O 3). Measurements on a Vibrating Sample Magnetometer showed an overall paramagnetic response behavior of the composite particles. Fluorescence spectroscopy showed fluorescent spectra typical for the Eu ion in a Gd 2O 3 host with a narrow emission peak centered near 615 nm. Our synthesis method provides a low-cost, high-rate synthesis that allows a wide range of biological applications of magnetic/fluorescent core/shell particles. We show an immunoassay using the fluorescent properties of the particles.",
author = "D. Dosev and M. Nichkova and R. Dumas and K. Liu and Kennedy, {I. M.}",
year = "2005",
language = "English (US)",
pages = "11352--11364",
booktitle = "AIChE Annual Meeting, Conference Proceedings",

}

TY - GEN

T1 - Spray pyrolysis synthesis of particles possessing magnetic and fluorescent properties. Application of magnetic/fluorescent particles in immunoassays

AU - Dosev, D.

AU - Nichkova, M.

AU - Dumas, R.

AU - Liu, K.

AU - Kennedy, I. M.

PY - 2005

Y1 - 2005

N2 - Many types of fluorescent nanoparticles have been synthesized as alternatives to organic dyes in biochemistry. Magnetic beads also have a long history of biological applications. In this work we apply flame spray pyrolysis in order to engineer a novel type of particle that has both fluorescent and magnetic properties. The particles have magnetic cores of iron oxide and a fluorescent shell of europium - doped gadolinium oxide (Eu:Gd 2O 3). Measurements on a Vibrating Sample Magnetometer showed an overall paramagnetic response behavior of the composite particles. Fluorescence spectroscopy showed fluorescent spectra typical for the Eu ion in a Gd 2O 3 host with a narrow emission peak centered near 615 nm. Our synthesis method provides a low-cost, high-rate synthesis that allows a wide range of biological applications of magnetic/fluorescent core/shell particles. We show an immunoassay using the fluorescent properties of the particles.

AB - Many types of fluorescent nanoparticles have been synthesized as alternatives to organic dyes in biochemistry. Magnetic beads also have a long history of biological applications. In this work we apply flame spray pyrolysis in order to engineer a novel type of particle that has both fluorescent and magnetic properties. The particles have magnetic cores of iron oxide and a fluorescent shell of europium - doped gadolinium oxide (Eu:Gd 2O 3). Measurements on a Vibrating Sample Magnetometer showed an overall paramagnetic response behavior of the composite particles. Fluorescence spectroscopy showed fluorescent spectra typical for the Eu ion in a Gd 2O 3 host with a narrow emission peak centered near 615 nm. Our synthesis method provides a low-cost, high-rate synthesis that allows a wide range of biological applications of magnetic/fluorescent core/shell particles. We show an immunoassay using the fluorescent properties of the particles.

UR - http://www.scopus.com/inward/record.url?scp=33645647556&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645647556&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:33645647556

SP - 11352

EP - 11364

BT - AIChE Annual Meeting, Conference Proceedings

ER -