Abstract
Many types of fluorescent nanoparticles have been synthesized as alternatives to organic dyes in biochemistry. Magnetic beads also have a long history of biological applications. In this work we apply flame spray pyrolysis in order to engineer a novel type of particle that has both fluorescent and magnetic properties. The particles have magnetic cores of iron oxide and a fluorescent shell of europium - doped gadolinium oxide (Eu:Gd 2O 3). Measurements on a Vibrating Sample Magnetometer showed an overall paramagnetic response behavior of the composite particles. Fluorescence spectroscopy showed fluorescent spectra typical for the Eu ion in a Gd 2O 3 host with a narrow emission peak centered near 615 nm. Our synthesis method provides a low-cost, high-rate synthesis that allows a wide range of biological applications of magnetic/fluorescent core/shell particles. We show an immunoassay using the fluorescent properties of the particles.
| Original language | English (US) |
|---|---|
| Title of host publication | AIChE Annual Meeting, Conference Proceedings |
| Pages | 11352-11364 |
| Number of pages | 13 |
| State | Published - 2005 |
| Event | 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase - Cincinnati, OH, United States Duration: Oct 30 2005 → Nov 4 2005 |
Other
| Other | 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase |
|---|---|
| Country | United States |
| City | Cincinnati, OH |
| Period | 10/30/05 → 11/4/05 |
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ASJC Scopus subject areas
- Engineering(all)
Cite this
Spray pyrolysis synthesis of particles possessing magnetic and fluorescent properties. Application of magnetic/fluorescent particles in immunoassays. / Dosev, D.; Nichkova, M.; Dumas, R.; Liu, K.; Kennedy, I. M.
AIChE Annual Meeting, Conference Proceedings. 2005. p. 11352-11364.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Spray pyrolysis synthesis of particles possessing magnetic and fluorescent properties. Application of magnetic/fluorescent particles in immunoassays
AU - Dosev, D.
AU - Nichkova, M.
AU - Dumas, R.
AU - Liu, K.
AU - Kennedy, I. M.
PY - 2005
Y1 - 2005
N2 - Many types of fluorescent nanoparticles have been synthesized as alternatives to organic dyes in biochemistry. Magnetic beads also have a long history of biological applications. In this work we apply flame spray pyrolysis in order to engineer a novel type of particle that has both fluorescent and magnetic properties. The particles have magnetic cores of iron oxide and a fluorescent shell of europium - doped gadolinium oxide (Eu:Gd 2O 3). Measurements on a Vibrating Sample Magnetometer showed an overall paramagnetic response behavior of the composite particles. Fluorescence spectroscopy showed fluorescent spectra typical for the Eu ion in a Gd 2O 3 host with a narrow emission peak centered near 615 nm. Our synthesis method provides a low-cost, high-rate synthesis that allows a wide range of biological applications of magnetic/fluorescent core/shell particles. We show an immunoassay using the fluorescent properties of the particles.
AB - Many types of fluorescent nanoparticles have been synthesized as alternatives to organic dyes in biochemistry. Magnetic beads also have a long history of biological applications. In this work we apply flame spray pyrolysis in order to engineer a novel type of particle that has both fluorescent and magnetic properties. The particles have magnetic cores of iron oxide and a fluorescent shell of europium - doped gadolinium oxide (Eu:Gd 2O 3). Measurements on a Vibrating Sample Magnetometer showed an overall paramagnetic response behavior of the composite particles. Fluorescence spectroscopy showed fluorescent spectra typical for the Eu ion in a Gd 2O 3 host with a narrow emission peak centered near 615 nm. Our synthesis method provides a low-cost, high-rate synthesis that allows a wide range of biological applications of magnetic/fluorescent core/shell particles. We show an immunoassay using the fluorescent properties of the particles.
UR - http://www.scopus.com/inward/record.url?scp=33645647556&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33645647556&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:33645647556
SP - 11352
EP - 11364
BT - AIChE Annual Meeting, Conference Proceedings
ER -