Several cases of wasting disease and dyspnea occurred in outbred Crl: CDI(ICR) nu/nu mice obtained recently from a commercial supplier. Gross necropsy revealed pulmonary consolidation, and histologically there was alveolar-wall thickening and filling of alveoli with macrophages and honey-combed eosinophilic material. Electron microscopic examination of lung tissue confirmed infection with Pneumocystis carinii.
|Original language||English (US)|
|Number of pages||5|
|Journal||Laboratory Animal Science|
|State||Published - Apr 1986|
ASJC Scopus subject areas
- Animal Science and Zoology