Spontaneous wasting disease in nude mice associated with Pneumocystis carinii infection.

E. C. Weir, D. G. Brownstein, Stephen W Barthold

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Several cases of wasting disease and dyspnea occurred in outbred Crl: CDI(ICR) nu/nu mice obtained recently from a commercial supplier. Gross necropsy revealed pulmonary consolidation, and histologically there was alveolar-wall thickening and filling of alveoli with macrophages and honey-combed eosinophilic material. Electron microscopic examination of lung tissue confirmed infection with Pneumocystis carinii.

Original languageEnglish (US)
Pages (from-to)140-144
Number of pages5
JournalLaboratory Animal Science
Volume36
Issue number2
StatePublished - Apr 1986
Externally publishedYes

Fingerprint

Pneumocystis Infections
Wasting Syndrome
wasting syndrome
Pneumocystis carinii
Macrophages
Nude Mice
Consolidation
Microscopic examination
lungs
Tissue
Lung
Honey
Electrons
dyspnea
mice
honey
infection
Dyspnea
necropsy
macrophages

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Spontaneous wasting disease in nude mice associated with Pneumocystis carinii infection. / Weir, E. C.; Brownstein, D. G.; Barthold, Stephen W.

In: Laboratory Animal Science, Vol. 36, No. 2, 04.1986, p. 140-144.

Research output: Contribution to journalArticle

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