Spontaneous wasting disease in nude mice associated with Pneumocystis carinii infection.

E. C. Weir, D. G. Brownstein, Stephen W Barthold

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Several cases of wasting disease and dyspnea occurred in outbred Crl: CDI(ICR) nu/nu mice obtained recently from a commercial supplier. Gross necropsy revealed pulmonary consolidation, and histologically there was alveolar-wall thickening and filling of alveoli with macrophages and honey-combed eosinophilic material. Electron microscopic examination of lung tissue confirmed infection with Pneumocystis carinii.

Original languageEnglish (US)
Pages (from-to)140-144
Number of pages5
JournalLaboratory Animal Science
Volume36
Issue number2
StatePublished - Apr 1986
Externally publishedYes

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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