Spontaneous wasting disease in nude mice associated with Pneumocystis carinii infection.

E. C. Weir; D. G. Brownstein; Stephen W Barthold

Spontaneous wasting disease in nude mice associated with Pneumocystis carinii infection.

E. C. Weir, D. G. Brownstein, Stephen W Barthold

Research output: Contribution to journal › Article › peer-review

Abstract

Several cases of wasting disease and dyspnea occurred in outbred Crl: CDI(ICR) nu/nu mice obtained recently from a commercial supplier. Gross necropsy revealed pulmonary consolidation, and histologically there was alveolar-wall thickening and filling of alveoli with macrophages and honey-combed eosinophilic material. Electron microscopic examination of lung tissue confirmed infection with Pneumocystis carinii.

Original language	English (US)
Pages (from-to)	140-144
Number of pages	5
Journal	Laboratory Animal Science
Volume	36
Issue number	2
State	Published - Apr 1986
Externally published	Yes

ASJC Scopus subject areas

Animal Science and Zoology
veterinary(all)

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title = "Spontaneous wasting disease in nude mice associated with Pneumocystis carinii infection.",

abstract = "Several cases of wasting disease and dyspnea occurred in outbred Crl: CDI(ICR) nu/nu mice obtained recently from a commercial supplier. Gross necropsy revealed pulmonary consolidation, and histologically there was alveolar-wall thickening and filling of alveoli with macrophages and honey-combed eosinophilic material. Electron microscopic examination of lung tissue confirmed infection with Pneumocystis carinii.",

author = "Weir, {E. C.} and Brownstein, {D. G.} and Barthold, {Stephen W}",

year = "1986",

month = apr,

language = "English (US)",

volume = "36",

pages = "140--144",

journal = "Comparative Medicine",

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publisher = "American Association for Laboratory Animal Science",

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AU - Brownstein, D. G.

AU - Barthold, Stephen W

PY - 1986/4

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N2 - Several cases of wasting disease and dyspnea occurred in outbred Crl: CDI(ICR) nu/nu mice obtained recently from a commercial supplier. Gross necropsy revealed pulmonary consolidation, and histologically there was alveolar-wall thickening and filling of alveoli with macrophages and honey-combed eosinophilic material. Electron microscopic examination of lung tissue confirmed infection with Pneumocystis carinii.

AB - Several cases of wasting disease and dyspnea occurred in outbred Crl: CDI(ICR) nu/nu mice obtained recently from a commercial supplier. Gross necropsy revealed pulmonary consolidation, and histologically there was alveolar-wall thickening and filling of alveoli with macrophages and honey-combed eosinophilic material. Electron microscopic examination of lung tissue confirmed infection with Pneumocystis carinii.

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