Spontaneous Occurrence of Hepatic Lipidosis in a Group of Laboratory Cats

Vincent Biourge, Paul Pion, Julia Lewis, James Morris, Quinton Rogers

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12 Scopus citations


Clinical signs consistent with hepatic lipidosis occurred in six obese adult laboratory cats, housed in a group cage, 6 to 7 weeks after changing their diet from a commercial to a purified diet. The affected cats lost 30 to 40% of their body weight in this time period. This rate of weight loss is compatible with little or no food intake. For treatment, 5 cats were tube‐fed three or four times daily with a high‐fat liquid diet supplemented with L‐citrulline and choline. All cats tolerated the diet, which contained 35% protein on an energy basis. Substantial voluntary food intake resumed 12 to 16 days after initiating treatment. The sixth cat was euthanatized. These observations suggest that 6 to 7 weeks of anorexia, associated with 30 to 40% weight loss, can induce hepatic lipidosis in obese but otherwise healthy cats, and confirm that with appropriate management the prognosis for cats with hepatic lipidosis is favorable.

Original languageEnglish (US)
Pages (from-to)194-197
Number of pages4
JournalJournal of Veterinary Internal Medicine
Issue number3
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • veterinary(all)


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